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Research Journal of Medicinal Plants
  Year: 2020 | Volume: 14 | Issue: 2 | Page No.: 43-52
DOI: 10.3923/rjmp.2020.43.52
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Influence of Altitude on Secondary Metabolites and Antioxidant Activity of Coleus forskohlii Root Extracts
Pawan Singh Rana , Pooja Saklani and Chandresh Chandel

Background and Objectives: Secondary metabolites like phenols, flavonoids and terpenoids plays an important role in plants defense system against free radicals. Increasing altitude magnifies the intensity of UV radiation and the decreasing temperature results in stressful conditions for the plants. Coleus forskohlii is a well-known medicinal plant that grows along a wide altitudinal range of 500-2300 m. Considering the globally accepted medicinal value of Coleus forskohlii, the aim of the study was to evaluate the effect of altitudes on the production of secondary metabolites and antioxidant activity in the wild populations. Materials and Methods: The plant samples were collected from 5 different locations of varying altitudes viz., Srinagar (606 m), Rudraprayag (727 m), Gopeshwar (1488 m), Pipalkoti (1339 m) and Joshimath (1986 m) in the Garhwal region of Uttarakhand, India. Standard spectrophotometric methods were employed to determine the total phenolic, flavonoid, terpenoid content and antioxidant activity of the plant roots. Results: A significant increase (p<0.05) was observed in the phenol, flavonoid and terpenoid content with the increasing altitude. The highest value for phenols was observed in the sample collected from Joshimath (1986 m) and similar trends were reported for flavonoids, terpenoids and antioxidant activity as well. The neighbor joining cluster and principal component analysis also confirms the high altitude population as better cultivar. Conclusion: The study confirms that change in growing altitudes affects the quantity of secondary metabolites in Coleus forskohlii as well as its antioxidant potential. Thus, the wild populations of Coleus forskohlii from a higher altitude may serve better in order to grow it and to exploit its therapeutic potential.
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How to cite this article:

Pawan Singh Rana, Pooja Saklani and Chandresh Chandel, 2020. Influence of Altitude on Secondary Metabolites and Antioxidant Activity of Coleus forskohlii Root Extracts. Research Journal of Medicinal Plants, 14: 43-52.

DOI: 10.3923/rjmp.2020.43.52








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