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Research Journal of Medicinal Plants
  Year: 2017 | Volume: 11 | Issue: 1 | Page No.: 19-24
DOI: 10.3923/rjmp.2017.19.24
 
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Chemical Constituents and Inhibition Xanthine Oxidase Activity of Avicennia marina Exudate

Khairul Anam , Dwi Susilo, Dewi Kusrini and L.N.A. Agustina

Abstract:
Background and Objective: Avicennia marina is one of the mangrove species which have various properties in traditional medicine. Extracts of the leaves have anticancer and antiviral activity. Seeds have antimalarial activity. Stems and fruit used as a cure rheumatism, skin diseases and inflammatory. While, the tree exudates efficacious as contraceptives and gout medicine. Scientific support for the use of exudates in traditional medicine is relatively limited. The purpose of this study is the verification of the use of A. marina exudate as lowering uric acid levels. Materials and Methods: In this study, analyzed the content of chemical, anti-hiperurisemia activity test by inhibiting the enzyme xanthine oxidase method toward extract and fractions of A. marina exudate and identification of the primary chemical compounds in the active fraction. Results: The results showed that the A. marina exudate containing flavonoids, tannins, quinones, saponins and steroid/triterpenoid. Ethanol extract of A. marina exudate has anti-hiperurisemia activity (IC50 = 202.4 ppm) and their ethyl acetic fraction (IC50 = 0.42 ppm) had stronger activity than the total extract. Conclusion: The identification results of component in the active by UV-vis spectrometer and FTIR thought to contain 5,7,3',4' tetrahidroxyflavone (Luteolin).
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How to cite this article:

Khairul Anam, Dwi Susilo, Dewi Kusrini and L.N.A. Agustina, 2017. Chemical Constituents and Inhibition Xanthine Oxidase Activity of Avicennia marina Exudate. Research Journal of Medicinal Plants, 11: 19-24.

DOI: 10.3923/rjmp.2017.19.24

URL: https://scialert.net/abstract/?doi=rjmp.2017.19.24

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