• [email protected]
  • +971 507 888 742
Submit Manuscript
SciAlert
  • Home
  • Journals
  • Information
    • For Authors
    • For Referees
    • For Librarian
    • For Societies
  • Contact
  1. Research Journal of Medicinal Plants
  2. Vol 9 (6), 2015
  3. 275-283
  • Online First
  • Current Issue
  • Previous Issues
  • More Information
    Aims and Scope Editorial Board Guide to Authors Article Processing Charges
    Submit a Manuscript

Research Journal of Medicinal Plants

Year: 2015 | Volume: 9 | Issue: 6 | Page No.: 275-283

Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Article Trend



Total views 697

Search


Authors


Chinyere V. Ilodibia

Country: Nigeria

Rachael U. Ugwu

Country: Nigeria

Onyinye L. Nwokolo

Country: Nigeria

Maureen U. Chukwuma

Country: Nigeria

Ebele E. Akachukwu

Country: Nigeria

Keywords


  • Antifungal
  • antibacterial
  • ethanol
  • aqueous
  • Gnetum africanum
  • fungal strains
  • bacterial strains
Research Article

Phytochemical Screening, Antifungal and Antibacterial Activity of Aqueous and Ethanolic Leaf and Stem Extracts of Gnetum africanum Welw

Chinyere V. Ilodibia, Rachael U. Ugwu, Onyinye L. Nwokolo, Maureen U. Chukwuma and Ebele E. Akachukwu
Aqueous and ethanolic leaf and stem extracts of Gnetum africanum were investigated for the presence and composition of these phytochemicals (alkaloid, flavonoid, tannin, phenol, saponin, sterol, terpenoid and cyanogenic glycoside) and their antifungal and antibacterial activities at various concentrations against some selected clinical microbes (fungal strains: Candida albicans and Aspergillus niger and bacterial strains: Staphylococcus aureus, Escherichia coli and Salmonella typhi) using standard methods. Analysis of variance (ANOVA) was employed in data analysis. Qualitative and percent quantitative phytochemical results showed that both the aqueous and ethanolic leaf and stem extracts contained these phytochemicals assayed but at varied quantities except cyanogenic glycoside. Antifungal and antibacterial studies indicated that both the aqueous and ethanolic leaf and stem extracts of Gnetum africanum inhibited the growth of the microbes but at varied levels and the inhibition was extracts concentration dependent. However, both the aqueous and ethanolic leaf and stem extracts showed no inhibition against the bacterial strains at 50 mg mL‾1 of the extracts. The extracts showed higher inhibition against the fungal strains than the bacterial strains. Inhibitory effect of the leaf extract was significantly higher than those of the stem extract. The ethanol extract showed significantly higher inhibition than the aqueous extract. Antibiotics had a better activity when compared to the extracts at the same concentration. Gnetum africanum extracts were biostatic in their action, when purified will give a product with higher activity. The data obtained from the study indicated that the plant possessed antifungal and antibacterial potentials especially antifungal and could be used as natural fungicides.
PDF Fulltext XML References Citation

How to cite this article

Chinyere V. Ilodibia, Rachael U. Ugwu, Onyinye L. Nwokolo, Maureen U. Chukwuma and Ebele E. Akachukwu, 2015. Phytochemical Screening, Antifungal and Antibacterial Activity of Aqueous and Ethanolic Leaf and Stem Extracts of Gnetum africanum Welw. Research Journal of Medicinal Plants, 9: 275-283.

URL: https://scialert.net/abstract/?doi=rjmp.2015.275.283

Related Articles

In vitro Antimicrobial and Cytotoxic Activities of Leaves and Flowers Extracts from Lippia alba
Biochemical and Histological Changes Associated with Long Term Consumption of Gnetum africanum Welw. Leaves in Rats
Antimicrobial Activity of Seaweeds Against Multi Drug Resistant Strains
An Update on Pharmacology of Satureja Species; From Antioxidant, Antimicrobial, Antidiabetes and Anti-hyperlipidemic to Reproductive Stimulation

Leave a Comment


Your email address will not be published. Required fields are marked *

Useful Links

  • Journals
  • For Authors
  • For Referees
  • For Librarian
  • For Socities

Contact Us

Office Number 1128,
Tamani Arts Building,
Business Bay,
Deira, Dubai, UAE

Phone: +971 507 888 742
Email: [email protected]

About Science Alert

Science Alert is a technology platform and service provider for scholarly publishers, helping them to publish and distribute their content online. We provide a range of services, including hosting, design, and digital marketing, as well as analytics and other tools to help publishers understand their audience and optimize their content. Science Alert works with a wide variety of publishers, including academic societies, universities, and commercial publishers.

Follow Us
© Copyright Science Alert. All Rights Reserved