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Research Journal of Medicinal Plants
  Year: 2012 | Volume: 6 | Issue: 7 | Page No.: 500-510
DOI: 10.3923/rjmp.2012.500.510
 
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Antioxidant and Prebiotic Potential of Some Cucurbits

D. Sharma, I. Rawat and H.C. Goel

Abstract:
The GI tract of an individual which is inhabited by a large number of microbes, is under constant threat from pathogens and oxidative damage. In Indian system of medicine, several cucurbits have been widely documented for prophylactic and therapeutic purposes to ameliorate such situations. The total flavonoids, observed in the extract of three cucurbits, Lagenaria siceraria (Ls), Luffa cylindrica (Lc) and Cucurbita pepo (Cp), were 17.9±1.3, 6.3±0.2 and 2.1±0.5 mg g-1, respectively. The antioxidant activity, determined by DPPH assay, displayed that Ls, Cp and Lc had 77±1.3, 10±3 and 10±1.0% free radical scavenging activity, respectively. Reduction Potential (RP) assay revealed the antioxidant effects for Ls, Lc and Cp as 44±0.8, 22±.3 and 15±.8%, respectively. Maximum activity of quenching H2O2 was demonstrated by Lc (92±1%) as compared to Cp (78±2%) and Ls (76±1.6%). Antimicrobial activity of Lactobacillus rhamnosus measured through generation of inhibition zone against E. coli was augmented maximally in presence of Ls (4.4±0.3 cm), followed by Cp (4.2±.01 cm) and Lc (4.0±.03 cm). Biofilm formation by L. rhamnosus was maximally supported in presence of Lc (absorbance = 0.26±0) followed by Ls (0.21±.01) and Cp (0.20±.01). Thus, these dietary cucurbits showed appreciable antioxidant activity and enhance antimicrobial and barrier function of mucosa by L. rhamnosus and impart protection to gut without any toxic effects.
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How to cite this article:

D. Sharma, I. Rawat and H.C. Goel, 2012. Antioxidant and Prebiotic Potential of Some Cucurbits. Research Journal of Medicinal Plants, 6: 500-510.

DOI: 10.3923/rjmp.2012.500.510

URL: https://scialert.net/abstract/?doi=rjmp.2012.500.510

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