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Research Journal of Medicinal Plants
  Year: 2012 | Volume: 6 | Issue: 6 | Page No.: 461-465
DOI: 10.3923/rjmp.2012.461.465
 
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In vitro Evaluation of the Essential Oil Extract of Six Plant Species and Ivermectin on the Microfilaria Larva of Simulium yahense

J.K. Ebigwai, E. M. Ilondu, A.A. Markson and E. Ekeleme

Abstract:
A comparative laboratory bioassay of the essential oil extracts of M. koenigii (seed), Citrus paradisi (seed) and the leaves, stem barks and roots of Alstonia boonei, Alternanthera repens, Eclipta prostrata and Rothmannia longiflora and their combination were compared with ivermectin against the third infectious microfilaria larva of Simulium yahense. Bioassay test showed remarkable larvicidal properties for ivermectin and the plant species under study as they could induce significant mortalities at low and varying concentrations in the larva of S. yahense. The LC50 and LC90 values estimated for M. koenigii, Citrus paradisi, Alstonia boonei, Alternanthera repens, Eclipta prostrata, Rothmannia longiflora, their combination and ivermectin are 5.75 and 13.18, 8.38 and 15.49, 3.02 and 15.49, 2.472 and 9.33, 2.87 and 12.88, 2.93 and 13.49, 2.61 and 3.16 and 2.43 and 5.37 ppm, respectively. The study revealed that ivermectin and the combination of the plant extracts could induce 100% mortality of the larva at a dose dependent response.
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How to cite this article:

J.K. Ebigwai, E. M. Ilondu, A.A. Markson and E. Ekeleme, 2012. In vitro Evaluation of the Essential Oil Extract of Six Plant Species and Ivermectin on the Microfilaria Larva of Simulium yahense. Research Journal of Medicinal Plants, 6: 461-465.

DOI: 10.3923/rjmp.2012.461.465

URL: https://scialert.net/abstract/?doi=rjmp.2012.461.465

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