Free Radical Scavenging Property of Bombax ceiba Linn. Root


	Research Journal of Medicinal Plants
	Year: 2011 \| Volume: 5 \| Issue: 4 \| Page No.: 462-470 DOI: 10.3923/rjmp.2011.462.470

Free Radical Scavenging Property of Bombax ceiba Linn. Root

V. Jain, S.K. Verma, S.S. Katewa, S. Anandjiwala and B. Singh

Abstract: Silk cotton tree (Bombax ceiba Linn.) is a well known ethnomedicinal plant. Root of this plant was investigated for its antioxidant potential for the first time. Assessment of antioxidant activity was done using 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assay and Reducing power assay. Preliminary phytochemical screening of the roots showed presence of phenolics, tannins, flavonoids, steroids, saponins and cardiac glycosides. Methanolic extract of the roots showed high amount of phenolics (30.95% w/w) and tannins (15.45% w/w) and a very good DPPH radical scavenging activity (EC₅₀ of 15.07 μg) in a dose dependent manner. The extract showed dose-dependent reduction ability (Fe³⁺ to Fe²⁺ transformation) with a maximum absorbance of 1.11 at a concentration of 500 μg of the extract. Acute study in healthy human volunteers showed a significant (p<0.05) rise in total antioxidant status at the end of 4 h after administration of 3 g root powder. This strong in vitro and in vivo antioxidant potential of B. ceiba dry root powder validates its uses in diabetes mellitus and heart disease as described in the traditional medicine.

PDF Fulltext XML References Citation Report Citation

RELATED ARTICLES:

•	Antioxidant Properties and Phenolic Compounds in Methanolic Extracts of Eichhornia crassipes

•	Protective Effect of Silymarin on Human Erythrocyte Against Tert-butyl Hydroperoxide Induced Oxidative Stress in vitro

•	Purification and Characterization of Phenolic Compounds from the Leaves of Cnestis ferruginea (De Candolle): Investigation of Antioxidant Property

•	Anti Sickle Erythrocytes Haemolysis Properties and Inhibitory Effect of Anthocyanins Extracts of Trema orientalis (Ulmaceae) on the Aggregation of Human Deoxyhemoglobin S in vitro

How to cite this article:

V. Jain, S.K. Verma, S.S. Katewa, S. Anandjiwala and B. Singh, 2011. Free Radical Scavenging Property of Bombax ceiba Linn. Root. Research Journal of Medicinal Plants, 5: 462-470.

DOI: 10.3923/rjmp.2011.462.470

URL: https://scialert.net/abstract/?doi=rjmp.2011.462.470

COMMENT ON THIS PAPER

	Full Name:
	E-mail:
	Comments:

Navigation


		Online First
		Current Issue
		Previous Issues
		Editorial Board
		Submit a Manuscript
		Guide to Authors
		Subscribe to E-alerts

Indexed In


		ASCI-Database
		Asian Digital Library
		Google Scholar