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Research Journal of Medicinal Plants
  Year: 2011 | Volume: 5 | Issue: 3 | Page No.: 338-342
DOI: 10.3923/rjmp.2011.338.342
Local Anesthetic Effect of Citrullus colocynthis on Rana hexadactyla
T. Ramanathan, S. Gurudeeban and K. Satyavani

Local anesthetics are a well-known group of pharmaceutical agents used to relieve pain in specific parts of the organism, inhibiting propagation of signals along the nerves. The present study petroleum ether extract of Citrullus colocynthis was evaluated its local anesthetic activity in the animal frog Rana hexadactyla. Local anesthetics are intended to relieve pain by depressing or blocking the sensory nerves reversibly. Local anaesthetics block nerve conduction where applied locally to nerve tissue in appropriate concentration 1:10 and 1:100. They act on any part of the various systems and on every type of nerve fibre. Lumbar plexus anesthesia method (or) nerve block Anesthesia method is used to study the activity briefly. This study proves that the leaves are equally effective as that of the synthetic standard drug xyclocaine when placed in sciatic nerve. Further studies are warranted to compare the mechanism of action.
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  •    A Review on the Recent Advances in Pharmacological Studies on Medicinal Plants; Animal Studies are Done but Clinical Studies Needs Completing
  •    Plant Mediated Synthesis of Biomedical Silver Nanoparticles by Using Leaf Extract of Citrullus colocynthis
  •    Bitter Apple (Citrullus colocynthis): An Overview of Chemical Composition and Biomedical Potentials
How to cite this article:

T. Ramanathan, S. Gurudeeban and K. Satyavani, 2011. Local Anesthetic Effect of Citrullus colocynthis on Rana hexadactyla. Research Journal of Medicinal Plants, 5: 338-342.

DOI: 10.3923/rjmp.2011.338.342








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