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Research Journal of Medicinal Plants

Year: 2009 | Volume: 3 | Issue: 4 | Page No.: 141-145
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Authors

T.O. Oyesola

F.S. Oluwole

O.A. Oyesola

Keywords

Research Article

Effects of Croton penduliflorus Methanolic Extract on Intestinal Enzymes and Protein Content in Pregnant Rats

T.O. Oyesola, F.S. Oluwole and O.A. Oyesola
The seeds of Croton penduliflorus (Family Euphorbiaccea) are often used as a purgative. The physiological effects of the methanolic extract on some intestinal disaccharide splitting enzymes were investigated in pregnant rats using an in vivo study. The extract was administered orally at a dose of 550 mg kg-1 body weight during the three phases of pregnancy. The extract caused a significant increase in maltase activity in the three phases of pregnancy, a significant increase in total protein concentration in early and late pregnancy and a significant increase in albumin concentration in early and mid pregnancy (p<0.01). The extract also caused a significant increase in sucrase activity in early pregnancy and in lactase activity in mid pregnancy. The present data suggest that increase activity of disaccharidase brush border enzymes most especially sucrase show that the extract might be having hyperplastic (growth) effect on the small intestinal enzyme activities, there is possibility of increased nutrients to the pregnant rats and fetuses.
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How to cite this article

T.O. Oyesola, F.S. Oluwole and O.A. Oyesola, 2009. Effects of Croton penduliflorus Methanolic Extract on Intestinal Enzymes and Protein Content in Pregnant Rats. Research Journal of Medicinal Plants, 3: 141-145.

URL: https://scialert.net/abstract/?doi=rjmp.2009.141.145

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