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Biological Activity of Merremia emarginata Crude Extracts in Different Solvents |
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A.V. Babu,
R.S.C. Rao,
K.G. Kumar,
B.H. Babu and P.V.V. Satyanarayana |
Abstract:
The plant Merremia emarginata (Burm. f.) Hallier f., belongs to Convolvulaceae family. In traditional medicinal system, different parts of M. emarginata have been mentioned to be therapeutically used as deobstruent, diuretic, for cough, headache, neuralgia and rheumatism. In the present study, biological activities of different solvent extracts isolated from M. emarginata were tested. Hexane (IA), ethyl acetate (IB), methanol (IC) and aqueous methanol (25%) (ID) extracts of M. emarginata were examined. Antioxidant properties of the extracts were studied by DPPH (1,1-Diphenyl-2-Picrylhydrozyl) radical scavenging activity method and superoxide radical scavenging activity method. Methanol extract exhibited better antioxidant activity than other extracts with IC50 of 8.59 μg mL-1 in DPPH radical scavenging method. Methanol and hexane extracts exhibited α-amylase inhibitory activity with IC50 of 104.5 and 133.4 μg mL-1, respectively. Ethyl acetate extract showed cytotoxicity with ED50 of 34.29 μg mL-1 in brine shrimp lethality assay. The present study revealed that the extracts IB and IC of M. emarginata were found to be showed promising biological activities. Methanol extract of this plant might be use full for antioxidant and antiobesity activities with minimal toxicity.
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How to cite this article:
A.V. Babu, R.S.C. Rao, K.G. Kumar, B.H. Babu and P.V.V. Satyanarayana, 2009. Biological Activity of Merremia emarginata Crude Extracts in Different Solvents. Research Journal of Medicinal Plants, 3: 134-140.
DOI: 10.3923/rjmp.2009.134.140
URL: https://scialert.net/abstract/?doi=rjmp.2009.134.140
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| COMMENTS |
28 December, 2009
bhushan bhadan:
give me all information about this plant. (m. emarginata)
and which activity is perform on this plant till. |
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07 January, 2010
bhushan s. bhadan:
Thank you very much!
for providing information about this plant.
means Only 2-3 activity perform on this plant like:
antioxidant and antiobesity activities
spasmolytic action
general depressant action
Antimigraine activity is not perform?
Please give detail.
Also give pharmacognostic study of this plant. |
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08 January, 2010
hari babu bollikolla:
total activities for different extracts studied by us:
1.antioxidant 2. antiobesity 3. cytotoxicity 4. antiinflammatory 5. brineshrimp lethality activity.
now we are also doing chemical work on this plant for pure compounds.
thank you.
b.h.babu |
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05 March, 2010
bhushan bhadan:
please give chemical information of the plant. |
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07 March, 2010
b.h.babu:
dear sir,
the chemical work i.e. Isolation of the compounds from the plant was going on. after the completion of the work. i will send the data.
thank your interest on my paper.
thankning you.
with best regards,
b.h.babu,
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05 April, 2010
bhushan s. bhadan:
dear sir please give me all paper i.e activity perform on this plant and LD50 0f plant.
I am waiting for your rply. |
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08 June, 2011
mukesh patel:
sir ur work is too good...and i want to know about its phytochemical investigation, so plz help me and reply soon. |
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01 August, 2011
vasu abau.Ala:
Sir
Thanks For you r interest on my paper . the phyto chemical work is under investigation. we will inform you after completion of our work. with best regards. |
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08 January, 2012
swetha madugula:
sir ur work is good and i need some informatation about activities perform on this plant |
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