Eastern Ghats are highly significant in terms of its Biodiversity. Extensive field and literature survey of trees in Eastern Ghats yielded 560 tree taxa under 262 genera belonging to 80 families out of the estimated 2500 species of flowering plants in Eastern Ghats. Euphorbiaceae (66) followed by Rubiaceae (38), Moraceae (31), Lauraceae (26), Mimosaceae (24), Rutaceae (21), Verbenaceae (17), Meliaceae (16), Cordiaceae, Fabaceae (14), Ebenaceae, Oleaceae (13), Tiliaceae (12) are the largest families based on the species number. The dominant genera include Ficus with 25 species, Grewia, Acacia, Diospyros with12 and Terminalia 10. Endemic tree species distributed in different regions of Eastern Ghats are Acacia donaldi, Actinodaphne madraspatana, Alphonsea madraspatana, Albizia thompsonii, Boswellia ovalifoliolata, Bridelia cinerascens, Cordia domestica, Croton scabiosus, Dimorphocalyx kurnoolensis, Eriolaena lushingtonii, Hildegardia populifolia, Lasiococca comberi, Premna hamiltonii, Pterocarpus santalinus, Shorea tumbuggaia, Syzigium alternifolium, Terminalia pallida, Wendlandia gambleii, Vernonia shevaroyensis, Toona ciliata var. brevipetiolata etc. A brief account on topography, geology, climate, vegetation pattern, floristic analysis, distribution pattern of trees in various regions of Eastern Ghats are provided.