Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
Pakistan Journal of Nutrition
  Year: 2009 | Volume: 8 | Issue: 2 | Page No.: 148-150
DOI: 10.3923/pjn.2009.148.150
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail
The Effects of Cola Acuminata on Arterial Blood Pressure
E.N.S. Igbinovia, A.C. Ugwu, A.O. Nwaopara, H.O. Otamere and W.A. Adisa

Abstract:
Caffeine has been proven to be vasoactive and augments the release of calcium from sarcoplasmic reticulum. Interestingly, caffeine is the most active principle of Cola acuminata-commonly consumed in Nigeria. This study is designed to determine its effects on blood pressure using 20 Sprague dawley rats with an average weight of 150g. The animals were subdivided into 2 groups of 10 rats each (control and test groups). The control rats were fed with rat chow while the test groups were fed with salt diet that was prepared by adding 7.7g of salt to 92.3g of normal rats chow in order to achieve hypertension. Substance extraction was by chloroform extraction. With the extract, different levels of the substance concentration were prepared and subsequently infused in sequence to the test rats. The results showed that diastolic blood pressure was more responsive to changes in concentration of Cola acuminata extract with a significant concentration dependent increase in the arterial blood pressure of both the normotensive and hypertensive rats. Considering the fact that Cola acuminata consumption is part of our culture and the fact that some become addicted, it is our opinion therefore, that the need for efforts towards identifying the cardiovascular implications of caffeine containing consumables, can never be over emphasized.
PDF Fulltext XML References Citation Report Citation
How to cite this article:

E.N.S. Igbinovia, A.C. Ugwu, A.O. Nwaopara, H.O. Otamere and W.A. Adisa, 2009. The Effects of Cola Acuminata on Arterial Blood Pressure. Pakistan Journal of Nutrition, 8: 148-150.

DOI: 10.3923/pjn.2009.148.150

URL: https://scialert.net/abstract/?doi=pjn.2009.148.150

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 

       

       

Curve Bottom