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Pakistan Journal of Biological Sciences

Year: 2019 | Volume: 22 | Issue: 11 | Page No.: 537-544
DOI: 10.3923/pjbs.2019.537.544

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Authors


Doha Abdou  Mohamed

Doha Abdou Mohamed

LiveDNA: 20.18316

Hend Abass  Essa

Hend Abass Essa

LiveDNA: 20.23415

Rasha Salah  Mohamed

Rasha Salah Mohamed

LiveDNA: 20.24942

Keywords


  • Purslane oil
  • garden cress oil
  • hyperlipidemia
  • rats
  • high fat diet
Research Article

Purslane and Garden Cress Seeds as Source of Unconventional Edible Oils for Prevention of Hyperlipidemia

Doha Abdou Mohamed Doha Abdou  Mohamed's LiveDNA, Hend Abass Essa Hend Abass  Essa's LiveDNA and Rasha Salah Mohamed Rasha Salah  Mohamed's LiveDNA
Background and Objective: Hyperlipidemia (HLP) is a leading cause for cardiovascular disease and atherosclerosis. Insufficient physical activity and unhealthy diet plays an important role in the progression of HLP. The present study was conducted to investigate the protective effect of 2 unconventional edible oils (purslane and garden cress) on hyperlipidemia. Materials and Methods: Diet high in fat and cholesterol was used as inducer of hyperlipidemia in rats for 5 weeks. Plasma and hepatic lipid profile were assessed. Plasma levels of malondialdehyde (MDA) as lipid peroxidation indicator was determined. Liver transaminases (AST and ALT) as liver function indicator and kidney function (creatinine and urea) were evaluated. Results: Results clarified significant elevation in plasma and liver lipid profiles, MDA, liver enzymes (AST and ALT) and kidney function (creatinine and urea) in hyperlipidemic control compared to normal control. Supplementation with purslane and garden cress seeds oils either in diet or oral showed significant improvement in all the studied parameters. Conclusion: Purslane and garden cress oils investigated in the current study produced significant reduction and elevation in bad and good cholesterol, respectively in plasma. Also both oils reduced hepatic lipid accumulation effectively in hyperlipidemia model in rats. Oils administration reduced plasma malondialdehyde and improves liver and kidney functions.
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How to cite this article

Doha Abdou Mohamed, Hend Abass Essa and Rasha Salah Mohamed, 2019. Purslane and Garden Cress Seeds as Source of Unconventional Edible Oils for Prevention of Hyperlipidemia. Pakistan Journal of Biological Sciences, 22: 537-544.

DOI: 10.3923/pjbs.2019.537.544

URL: https://scialert.net/abstract/?doi=pjbs.2019.537.544

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