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Pakistan Journal of Biological Sciences
  Year: 2019 | Volume: 22 | Issue: 5 | Page No.: 226-230
DOI: 10.3923/pjbs.2019.226.230
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Impact of Khat (Catha edulis) Chewing on Carotid Intima-media Thickness

Moawia Gameraddin , Bushra Abdalmalik, Mohamed Ibrahim, Mustafa Mahmoud and Sultan A. Alshoabi

Background and Objective: Khat has severe adverse socio-economic consequences. It causes serious cardiovascular, neurological and psychiatric problems. The study aimed to evaluate the effect of chewing khat on intima-media thickness (IMT) of the common carotid arteries. Materials and Methods: This was a descriptive case-control cross-sectional study. A total of 50 participants of chronic regular khat chewers were investigated. B-mode ultrasound 7-10 MHz linear transducers used for assessment of common carotid arteries according to the standard carotid sonography protocol. The IMT was measured and the presence of plaques was assessed. Results: The carotid IMT was significantly increased in regular khat chewers more than the controls (p-value = 0.016). The common carotid IMT increased in smokers more than non-smokers among khat chewers (0.6710±0.20687 vs. 0.5789±0.16859 mm). Significant correlations existed between the duration of chewing khat and age with the presence of plaque (p-values = 0.013 and 0.002, respectively). Conclusion: There is a significant correlation between carotid plaque and longtime khat chewing. Khat is a contributory factor for increasing carotid intima-media thickness and formation of carotid plaques. A combination of khat and smoking produce more thickening of carotid intima-media.
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  •    Doppler Assessment of the Effect of Chewing Qat on Hemodynamics of the Common Carotid Arteries
How to cite this article:

Moawia Gameraddin, Bushra Abdalmalik, Mohamed Ibrahim, Mustafa Mahmoud and Sultan A. Alshoabi, 2019. Impact of Khat (Catha edulis) Chewing on Carotid Intima-media Thickness. Pakistan Journal of Biological Sciences, 22: 226-230.

DOI: 10.3923/pjbs.2019.226.230






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