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Pakistan Journal of Biological Sciences
  Year: 2014 | Volume: 17 | Issue: 12 | Page No.: 1231-1236
DOI: 10.3923/pjbs.2014.1231.1236
 
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Antimutagenic and Anticancer Activity of Al Madinah Alhasawy Mint (Mentha longifolia) Leaves Extract

Khalil Al-Ali, Mohamad Abdelrazik, Abdulaziz Alghaithy, Atef Diab, Hesham El-Beshbishy and Hussam Baghdadi

Abstract:
Mentha is one of the genera of Lamiaceae family. The aim of the present study was to evaluate the antimutagenic and anticancer activity of the water and methanolic extract of Alhasawy mint (Mentha longifolia), that grown in Madina Province, western region, Saudi Arabia using three different bioassays namely; Brine shrimp bioassay, Ames mutagenicity bioassay using 3 Hist-Salmonella typhimurium strains of different mutations (TA98, TA97 and TA100) and 2 reference mutagenic drugs nitrosopiperidine (NP) and 2-amino-3-methylimidazo-quinolidine (IQ) and Mammalian cell lines bioassays using 2 different cell lines HepG2 and Vero cell lines. The plant extract showed an efficient antimutagenic activity against the studied bioassays in a directly proportional effect with concentration.
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How to cite this article:

Khalil Al-Ali, Mohamad Abdelrazik, Abdulaziz Alghaithy, Atef Diab, Hesham El-Beshbishy and Hussam Baghdadi, 2014. Antimutagenic and Anticancer Activity of Al Madinah Alhasawy Mint (Mentha longifolia) Leaves Extract. Pakistan Journal of Biological Sciences, 17: 1231-1236.

DOI: 10.3923/pjbs.2014.1231.1236

URL: https://scialert.net/abstract/?doi=pjbs.2014.1231.1236

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