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Pakistan Journal of Biological Sciences
  Year: 2013 | Volume: 16 | Issue: 15 | Page No.: 747-750
DOI: 10.3923/pjbs.2013.747.750
 
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Prevalence of Hepatitis B Infection in Rheumatoid Arthritis Patients

Gholam Hossein Alishiri, Gholam Ali Ghorbani and Salimzadeh Ahmad

Abstract:
Rheumatoid arthritis is a progressive and destructive inflammatory disease of the joints. They had increased mortality depend to use of immunosuppressive drugs. Hepatitis B virus infection is also a health problem in the world. Iran is moderate prevalence endemic area for Hepatitis B virus and it is come too reduced recently by children vaccination. Aim of this study is determined prevalence and screening of Hepatitis B virus infection in rheumatoid arthritis patients. This study is a descriptive cross-sectional which all patients with rheumatic arthritis recruited to study in Tehran in 2012. Then HbsAg and HbcAb assayed for each subjects. In 268 rheumatoid arthritis patients which (82.2%) were female and the average age is 46±14 years old. HbsAg and HbcAb were positive in 4(1.49%) and 9(3.35%), respectively. Only between duration of rheumatoid arthritis and HbcAb had significant association (p<0.014). The present study highlights Rheumatoid arthritis patients treated with immunosuppressive drugs are at increased risk to reactivation of hepatitis B virus, so screening for Hepatitis B virus infection should be performed prior to immunosuppressive therapy.
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How to cite this article:

Gholam Hossein Alishiri, Gholam Ali Ghorbani and Salimzadeh Ahmad, 2013. Prevalence of Hepatitis B Infection in Rheumatoid Arthritis Patients. Pakistan Journal of Biological Sciences, 16: 747-750.

DOI: 10.3923/pjbs.2013.747.750

URL: https://scialert.net/abstract/?doi=pjbs.2013.747.750

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