Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
Pakistan Journal of Biological Sciences
  Year: 2012 | Volume: 15 | Issue: 6 | Page No.: 301-305
DOI: 10.3923/pjbs.2012.301.305
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail
Sub-chronic Concomitant Ingestion of L-arginine and Monosodium Glutamate Improves Feed Efficiency, Lipid Metabolism and Antioxidant Capacity in Male Wistar Rats
Anthony C. Cemaluk Egbuonu

Abstract:
The use of L-arginine (ARG) is common in supplements, whereas, Monosodium Glutamate (MSG) is widely used as flavor enhancing food additive. Thus, ARG and MSG may be present together in human diets, warranting this study aimed at investigating the effect of concomitant ingestion of ARG and MSG on some biochemical indices in male rats. Twelve male albino rats were grouped into three (n = 4) and concomitantly exposed to 0:0, 20:5 and 60:15 mg kg-1 of ARG:MSG. Exposure was peroral and every twenty four h for 28 days. ARG plus MSG treatment caused a significant (p≤0.05) increase in Feed Efficiency (FE) (Low dose: 5.23±22%; High dose: 5.60±11%), whereas, it decreased (p≤0.05) the serum Total Cholesterol (T-Chol) (low dose: 80.83±0.11 mg/100 mL, high dose: 92.55±0.14 mg/100 mL), triacylglycerol (TAG) (low dose: 179.91±0.09 mg/100 mL, high dose: 119.77±0.32 mg/100 mL) and malondialdehyde (MDA) (low dose: 5.00±0.07 mg/100 mL, high dose: 24.36±0.10 mg/100 mL) concentrations of the rats in a dose dependent manner. However, (at the high dose) the increase in Body Weight (BW) (0.08±0.07 kg), Feed Intake (FI) (0.40±0.03 kg) and Water Intake (WI) (0.65±0.18 L) induced by ARG plus MSG exposure was not significant (p≥0.05), suggesting non treatment related effect on these routine parameters. However, exposure to ARG plus MSG may significantly improve feed efficiency, lipid metabolism and antioxidant capacity in the male rats.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Comparative Assessment of some Mineral, Amino Acid and Vitamin Compositions of Watermelon (Citrullus lanatus) Rind and Seed
  •    Cardiovascular Risks and Impaired Lipid Metabolism in Asymptomatic Petroleum Depot Workers in Calabar Metropolis, Nigeria
  •    Effect of L-Arginine on Some Biochemical Markers of Metabolic Syndrome Associated with Brain Function in Female Wistar Rats
  •    Alterations in the Liver Histology and Markers of Metabolic Syndrome Associated with Inflammation and Liver Damage in L-arginine Exposed Female Wistar Albino Rats
  •    Selenium and α-Difluromethylornthine in Combination have Strong Activity Against Elevated Polyamines and Glucose Levels in Serum
  •    Some Biochemical Effects of Sub-Acute Oral Administration of L-Arginine on Monosodium Glutamate-Fed Wistar Albino Rats 2: Serum Alkaline Phosphatase, Total Acid Phosphatase and Aspartate Aminotransferase Activities
  •    The Efficacy of L-arginine Gel for Treatment of Chronic Anal Fissure Compared to Surgical Sphincterotomy
  •    L-Arginine Ameliorates Arylesterase/Paraoxonase Activity of Paraoxonase-1 in Hypercholesterolemic Rats
How to cite this article:

Anthony C. Cemaluk Egbuonu , 2012. Sub-chronic Concomitant Ingestion of L-arginine and Monosodium Glutamate Improves Feed Efficiency, Lipid Metabolism and Antioxidant Capacity in Male Wistar Rats. Pakistan Journal of Biological Sciences, 15: 301-305.

DOI: 10.3923/pjbs.2012.301.305

URL: https://scialert.net/abstract/?doi=pjbs.2012.301.305

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 
 
 

       

       

Curve Bottom