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Pakistan Journal of Biological Sciences
  Year: 2011 | Volume: 14 | Issue: 19 | Page No.: 909-911
DOI: 10.3923/pjbs.2011.909.911
 
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Antinociceptive and Anti-inflammatory Activity of the Ethanolic Extract of Cymbidium aloifolium (L.)

Md. Amran Howlader, Mahmudul Alam, Kh. Tanvir Ahmed, Farjana Khatun and Apurba Sarker Apu

Abstract:
The ethanol leaf extract of Cymbidium aloifolium (L.) was evaluated for its analgesic and anti-inflammatory activities. The extract, at the dose of 200 and 400 mg kg-1 body weight, exerted the analgesic activity by observing the number of abdominal contractions and anti-inflammatory activity against Carrageenin induced paw edema in mice by measuring the paw volume. The ethanolic extract of Cymbidium aloifolium (L.) showed statistically significant (p<0.05) reduction of percentage of writhing of 33.57 and 61.31% at 200 and 400 mg kg-1 oral dose, respectively, when compared to negative control. The Ethanolic plant extract also showed significant (p<0.05) dose dependent reduction of mean increase of formation of paw edema. The results of the experiment and its statistical analysis showed that the ethanolic plant extract had shown significant (p<0.05) dose dependent analgesic and anti-inflammatory activities when compared to the control.
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How to cite this article:

Md. Amran Howlader, Mahmudul Alam, Kh. Tanvir Ahmed, Farjana Khatun and Apurba Sarker Apu, 2011. Antinociceptive and Anti-inflammatory Activity of the Ethanolic Extract of Cymbidium aloifolium (L.). Pakistan Journal of Biological Sciences, 14: 909-911.

DOI: 10.3923/pjbs.2011.909.911

URL: https://scialert.net/abstract/?doi=pjbs.2011.909.911

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