Submit Manuscript

Pakistan Journal of Biological Sciences

Year: 2011 | Volume: 14 | Issue: 10 | Page No.: 560-571
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Article Trend

Total views 809

Search

Authors

Witabouna Mamidou Kone

Kakou-Ngazoa E. Solange

Mireille Dosso

Keywords

Review Article

Assessing Sub-saharian Erythrina for Efficacy: Traditional uses, Biological Activities and Phytochemistry

Witabouna Mamidou Kone, Kakou-Ngazoa E. Solange and Mireille Dosso
The genus Erythrina comprises more than 100 species, widely distributed in tropical and subtropical areas. In Africa, 31 wild species and 14 cultivated species have been described. In sub-Saharan Africa, Erythrina species are used to treat frequent parasitic and microbial diseases, inflammation, cancer, wounds. The rationale of these traditional uses in African traditional medicine was established by screening several species for biological activities. Promising activities were found against bacteria, parasites (Plasmodium), human and phytopathogenic fungi, some of which were multidrug resistant (MDR) microorganisms. Some species also exhibited antioxidant, anti-inflammatory activities and enzymes inhibitory properties. Most of the species chemically investigated were reported to contain flavanones, prenylated isoflavones, isoflavanones and pterocarpans. Some phytochemicals (vogelin B, vogelin C, isowighteone, abyssinin II, derrone) were the active principles as antibacterials, antifungals, antiplasmodials and inhibitors of enzyme borne diseases (PTP1B, HIV protease, DGAT). This review highlights the important role of Erythrina species as sources of lead compounds or new class of phytotherapeutic agents for fighting against major public health (MDR infections, cancer, diabetes, obesity) in Sub-Saharan Africa.
PDF Fulltext XML References Citation

Related Articles

Antibacterial Activity and Phytochemical Study of Six Medicinal Plants used in Benin
Antioxidant and Antibacterial Activities of Two Combretum Species from Burkina Faso
Adulticidal Effects of Essential Oils Extracts from Capsicum annuum (Solanaceae) Piper nigrum (Piperaceae) and Zingiber officinale (Zingiberaceae) on Anopheles gambiae (Diptera-Culicidea), Vector of Malaria
Extraction of Insulin like Compounds from Bitter Melon Plants
In vitro Antioxidant Activities of Aqueous Extract of Ficus Bangalensis Linn. Root

Leave a Comment

Your email address will not be published. Required fields are marked *