• [email protected]
  • +971 507 888 742
Submit Manuscript
SciAlert
  • Home
  • Journals
  • Information
    • For Authors
    • For Referees
    • For Librarian
    • For Societies
  • Contact
  1. Pakistan Journal of Biological Sciences
  2. Vol 14 (1), 2011
  3. 41-46
  • Online First
  • Current Issue
  • Previous Issues
  • More Information
    Aims and Scope Editorial Board Guide to Authors Article Processing Charges
    Submit a Manuscript

Pakistan Journal of Biological Sciences

Year: 2011 | Volume: 14 | Issue: 1 | Page No.: 41-46
DOI: 10.3923/pjbs.2011.41.46

Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Article Trend



Total views 388

Search


Authors


R.Bt. Hashim

Country: Malaysia

S. Husin

Country: Malaysia

M.M. Rahman

Country: Malaysia

Keywords


  • Escherichia coli
  • drug resistance
  • Extended spectrum betalactamase
  • Klebsiella
  • polymerase chain reaction
Research Article

Detection of Betalactamase Producing Bacterial Genes and their Clinical Features

R.Bt. Hashim, S. Husin and M.M. Rahman
The present study was aimed to identify the gene of drug resistance betaclamase producing bacteria and clinical features of the infected patients at Hospital University Kebangsaan Malaysia. Blood samples from the patients were collected, processed and betalactamase producing drug resistance bacteria were identified by antibiotic sensitivity testing. Genes of the drug resistance bacteria were detected and characterized by polymerase chain reaction. A total of 34 isolates of drug resistance Betalactamase producing E.coli and Klebsiella spp. were isolated from 2,502 patients. Most common drug resistance gene TEM was found in 50% of the isolates. 11% was found positive for both TEM and SHV. Next 11% of the isolates expressed only SHV genes. Clinical features of the patients were recorded from where the bacteria isolated. Regarding community affiliations 70.5% of the infected patients were Malay 17.6% were Indian and 11.7% were Chinese. Majority of the patients has an underlying pre-morbid condition as reflected by their diagnosis. Better infection control and hygiene in hospitals, plus controlled and prudent use of antibiotics, is required to minimize the impact of drug resistance betalactamase producing bacteria and the spread of infections.
PDF Fulltext XML References Citation

How to cite this article

R.Bt. Hashim, S. Husin and M.M. Rahman, 2011. Detection of Betalactamase Producing Bacterial Genes and their Clinical Features. Pakistan Journal of Biological Sciences, 14: 41-46.

DOI: 10.3923/pjbs.2011.41.46

URL: https://scialert.net/abstract/?doi=pjbs.2011.41.46

Related Articles

High Prevalence of Multi-drug Resistant Bacteria in Selected Poultry Farms in Selangor, Malaysia

Leave a Comment


Your email address will not be published. Required fields are marked *

Useful Links

  • Journals
  • For Authors
  • For Referees
  • For Librarian
  • For Socities

Contact Us

Office Number 1128,
Tamani Arts Building,
Business Bay,
Deira, Dubai, UAE

Phone: +971 507 888 742
Email: [email protected]

About Science Alert

Science Alert is a technology platform and service provider for scholarly publishers, helping them to publish and distribute their content online. We provide a range of services, including hosting, design, and digital marketing, as well as analytics and other tools to help publishers understand their audience and optimize their content. Science Alert works with a wide variety of publishers, including academic societies, universities, and commercial publishers.

Follow Us
© Copyright Science Alert. All Rights Reserved