The Immune System which Adversely Alter Thyroid Functions: A Review on the Concept of Autoimmunity


	Pakistan Journal of Biological Sciences
	Year: 2010 \| Volume: 13 \| Issue: 16 \| Page No.: 765-774 DOI: 10.3923/pjbs.2010.765.774

The Immune System which Adversely Alter Thyroid Functions: A Review on the Concept of Autoimmunity

Azad Reza Mansourian

Abstract: The immune system protect individual from many pathogens exists within our environment and in human body, by destroying them through molecular and cellular mechanism of B and T cells of immune system. Autoimmunity is an adverse relation of immune system against non- foreign substances leaving behind either alters the normal function or destroying the tissue involved. Autoimmunity occur in genetically predispose persons with familial connections. The autoimmunity to the thyroid gland mainly consists of Hashimato thyroiditis and Grave's disease, the two end of spectrum in thyroid function of hypo and hyperactivity, respectively. The thyroid stimulating hormone receptor, thyroglobuline, enzymes of thyroid hormones synthesis are targeted by autoantibodies and cell- mediated reactions. The aim of this review is to explore the studies reported on the autoimmunity to the thyroid gland.

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How to cite this article:

Azad Reza Mansourian , 2010. The Immune System which Adversely Alter Thyroid Functions: A Review on the Concept of Autoimmunity. Pakistan Journal of Biological Sciences, 13: 765-774.

DOI: 10.3923/pjbs.2010.765.774

URL: https://scialert.net/abstract/?doi=pjbs.2010.765.774

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