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Pakistan Journal of Biological Sciences
  Year: 2010 | Volume: 13 | Issue: 16 | Page No.: 765-774
DOI: 10.3923/pjbs.2010.765.774
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The Immune System which Adversely Alter Thyroid Functions: A Review on the Concept of Autoimmunity

Azad Reza Mansourian

The immune system protect individual from many pathogens exists within our environment and in human body, by destroying them through molecular and cellular mechanism of B and T cells of immune system. Autoimmunity is an adverse relation of immune system against non- foreign substances leaving behind either alters the normal function or destroying the tissue involved. Autoimmunity occur in genetically predispose persons with familial connections. The autoimmunity to the thyroid gland mainly consists of Hashimato thyroiditis and Grave's disease, the two end of spectrum in thyroid function of hypo and hyperactivity, respectively. The thyroid stimulating hormone receptor, thyroglobuline, enzymes of thyroid hormones synthesis are targeted by autoantibodies and cell- mediated reactions. The aim of this review is to explore the studies reported on the autoimmunity to the thyroid gland.
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  •    A Review of Literature on Thyroid Hormone Disorders Originated from Extra Thyroidal Illness
  •    Liver Functional Behavior During Thyrotoxicosis: A Review
  •    Clinical Diagnostic Laboratory Play a Crucial Role in the Management of Thyroid Disorders: A Literature Review
  •    A Review of Literatures on the Adverse Effects of Thyroid Abnormalities and Liver Disorders: An Overview on Liver Dysfunction and Hypothyroidism
  •    The State of Serum Lipids Profiles in Sub-Clinical Hypothyroidism: A Review of the Literature
  •    A Survey of Urinary Iodine Concentration in South-east of Caspian Sea in Northern, Iran
How to cite this article:

Azad Reza Mansourian , 2010. The Immune System which Adversely Alter Thyroid Functions: A Review on the Concept of Autoimmunity. Pakistan Journal of Biological Sciences, 13: 765-774.

DOI: 10.3923/pjbs.2010.765.774






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