Subscribe Now Subscribe Today
Science Alert
Curve Top
Pakistan Journal of Biological Sciences
  Year: 2010 | Volume: 13 | Issue: 24 | Page No.: 1202-1207
DOI: 10.3923/pjbs.2010.1202.1207
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

The Hypolipidemic Effect of Citrullus colocynthis on Patients with Hyperlipidemia

A.R. Rahbar and I. Nabipour

Citrullus colocynthis is one of the medical herbs that traditionally have been used as an antidiabetic medication in tropical and subtropical countries. The aim of this study was to investigate the hypolipidemic effect of Citrullus colocynthis beyond the hypoglycemic impact on human. One hundred dislipidemic patients were randomly divided into two groups namely treated (n = 50) group and placebo (n = 50) group. The subjects were treated daily by powdered seeds of Citrullus colocynthis (300 mg) and placebo for 6 weeks. The serums, TG, Chol, LDL-C, HDL-C, SGOT and SGPT were measured with enzymatic methods at the beginning and the end of the project. The significance of differences within these groups was calculated by Paired T-test and by analysis of covariance between them. There were significant differences within and between treated and placebo groups during our treatment in TG and in Cholesterol after intervention (p<0.05). A daily intake of 300 mg day-1 of powdered seeds of Citrullus colocynthis can lower the triglyceride and cholesterol concentration significantly in nondiabetic hyperlipidemic patients.
PDF Fulltext XML References Citation Report Citation
  •    A Review on the Recent Advances in Pharmacological Studies on Medicinal Plants; Animal Studies are Done but Clinical Studies Needs Completing
  •    Screening of Antioxidant and Antiulcer Potential of Citrullus colocynthis Methanolic Seed Extract
  •    Re-Evaluation of Individual and Combined Garlic and Flaxseed Diets on Hyperlipidemic Rats
  •    Hypolipidaemic Effects of Citrullus colocynthis L. in Rabbits
  •    Clinical Study of Turmeric (Curcuma longa L.) and Garlic (Allium sativum L.) Extracts as Antihyperglycemic and Antihyperlipidemic Agent in Type-2 Diabetes-Dyslipidemia Patients
How to cite this article:

A.R. Rahbar and I. Nabipour, 2010. The Hypolipidemic Effect of Citrullus colocynthis on Patients with Hyperlipidemia. Pakistan Journal of Biological Sciences, 13: 1202-1207.

DOI: 10.3923/pjbs.2010.1202.1207






Curve Bottom