Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
Pakistan Journal of Biological Sciences
  Year: 2009 | Volume: 12 | Issue: 16 | Page No.: 1152-1155
DOI: 10.3923/pjbs.2009.1152.1155
Antimicrobial and Cytotoxic Activity of the Alkaloids of Amlaki (Emblica officinalis)
S. Rahman, M.M. Akbor, A. Howlader and A. Jabbar

Abstract:
Alkaloids are important sources of drug that’s why we have conducted our research to find out the biological activity of the alkaloids of a plant that is the Amlaki. Alkaloids were extracted from the methanolic extract of the fresh ripe fruits of Amlaki (Emblica officinalis) through solvent-solvent partitioning method with n-hexane and chloroform. The chloroform soluble fraction of the crude methanolic extract of the ripe fruits of Amlaki containing alkaloids was subjected to antimicrobial activity and brine shrimp lethality bioassay for observing cytotoxic activity. The chloroform soluble fraction of the methanolic extract exhibited significant antimicrobial activity against some Gram positive and Gram negative pathogenic bacteria and strong cytotoxicity having a LC50 of 10.257±0.770 μg mL-1. It is concluded that the chloroform soluble fraction of the ripe fruits of Amlaki containing alkaloids are biologically active.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Biotransformation of Gallotannins From Fresh Fruit Juice of Emblica officinalis in In-vitro System
  •    Plant as a Source of Natural Antiviral Agents
  •    Emblica officinalis Geart.: A Comprehensive Review on Phytochemistry, Pharmacology and Ethnomedicinal Uses
How to cite this article:

S. Rahman, M.M. Akbor, A. Howlader and A. Jabbar, 2009. Antimicrobial and Cytotoxic Activity of the Alkaloids of Amlaki (Emblica officinalis). Pakistan Journal of Biological Sciences, 12: 1152-1155.

DOI: 10.3923/pjbs.2009.1152.1155

URL: https://scialert.net/abstract/?doi=pjbs.2009.1152.1155

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 
 
 
 

       

       

Curve Bottom