Antimicrobial and Cytotoxic Activity of the Alkaloids of Amlaki (Emblica officinalis)


	Pakistan Journal of Biological Sciences
	Year: 2009 \| Volume: 12 \| Issue: 16 \| Page No.: 1152-1155 DOI: 10.3923/pjbs.2009.1152.1155

Antimicrobial and Cytotoxic Activity of the Alkaloids of Amlaki (Emblica officinalis)

S. Rahman, M.M. Akbor, A. Howlader and A. Jabbar

Abstract: Alkaloids are important sources of drug that’s why we have conducted our research to find out the biological activity of the alkaloids of a plant that is the Amlaki. Alkaloids were extracted from the methanolic extract of the fresh ripe fruits of Amlaki (Emblica officinalis) through solvent-solvent partitioning method with n-hexane and chloroform. The chloroform soluble fraction of the crude methanolic extract of the ripe fruits of Amlaki containing alkaloids was subjected to antimicrobial activity and brine shrimp lethality bioassay for observing cytotoxic activity. The chloroform soluble fraction of the methanolic extract exhibited significant antimicrobial activity against some Gram positive and Gram negative pathogenic bacteria and strong cytotoxicity having a LC₅₀ of 10.257±0.770 μg mL^-1. It is concluded that the chloroform soluble fraction of the ripe fruits of Amlaki containing alkaloids are biologically active.

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How to cite this article:

S. Rahman, M.M. Akbor, A. Howlader and A. Jabbar, 2009. Antimicrobial and Cytotoxic Activity of the Alkaloids of Amlaki (Emblica officinalis). Pakistan Journal of Biological Sciences, 12: 1152-1155.

DOI: 10.3923/pjbs.2009.1152.1155

URL: https://scialert.net/abstract/?doi=pjbs.2009.1152.1155

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