Prevalence of Epstein-Barr Virus Type 1 in Patients with Chronic Periodontitis by Nested-PCR


	Pakistan Journal of Biological Sciences
	Year: 2007 \| Volume: 10 \| Issue: 24 \| Page No.: 4547-4550 DOI: 10.3923/pjbs.2007.4547.4550

Prevalence of Epstein-Barr Virus Type 1 in Patients with Chronic Periodontitis by Nested-PCR

S.H. Moghim, M. Chalabi , A. Moghareh Abed , F. Rezaei and H. Tamizifar

Abstract: The present study evaluated the subgingival presence of Epstein-Barr virus type 1 (EBV-1) in patients with chronic periodontitis with nested-PCR. Subgingival plaque samples from 61 patients with chronic periodontitis with Probing Depth (PD) >= 6 and 40 healthy controls were collected by sterile curette. DNA was extracted. A nested Polymerase Chain Reaction (PCR) method determined presence of EBV-1. The study included 61 patients (34 women, 27 men; 24-69 years of age; mean 43) and 40 periodontally health controls (22 Women, 18 men, 21-69 years in age; mean 41.35%). EBV type 1 was detected in 37 samples (60.7%) and 1 samples (2.5%) of chronic periodontitis patients and healthy subjects, respectively. This study demonstrated that EBV-1 infection is associated with the activity of chronic periodontitis.

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How to cite this article:

S.H. Moghim, M. Chalabi , A. Moghareh Abed , F. Rezaei and H. Tamizifar , 2007. Prevalence of Epstein-Barr Virus Type 1 in Patients with Chronic Periodontitis by Nested-PCR. Pakistan Journal of Biological Sciences, 10: 4547-4550.

DOI: 10.3923/pjbs.2007.4547.4550

URL: https://scialert.net/abstract/?doi=pjbs.2007.4547.4550

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