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Pakistan Journal of Biological Sciences
  Year: 2007 | Volume: 10 | Issue: 1 | Page No.: 137-141
DOI: 10.3923/pjbs.2007.137.141
 
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The Hypoglycaemic Activity of the Aqueous Extract of Stachytarpheta angustifolia (Verbanaceae) in Normoglycaemic and Alloxan-Induced Diabetic Rats

A.B. Isah, Y.K.E. Ibrahim, E.M. Abdulrahman and M.A. Ibrahim

Abstract:
The hypoglycaemic activity of the aqueous extract of Stachytarpheta angustifolia (Verbanaceae) was studied in normoglycaemic and alloxan-induced diabetic rats. The extract was administered orally to the rats and blood glucose level was monitored for 7 h. Results indicate that the aqueous extract (750 mg kg-1) produced a significant blood glucose reduction in both normoglycaemic and alloxan-induced diabetic rats (p<0.05). The present result therefore appears to support the use of the plant aqueous extract for the management of type 2 diabetes by traditional medical practitioners in Northern Nigeria. The mechanism of action of the aqueous extract needs to be studied.
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How to cite this article:

A.B. Isah, Y.K.E. Ibrahim, E.M. Abdulrahman and M.A. Ibrahim, 2007. The Hypoglycaemic Activity of the Aqueous Extract of Stachytarpheta angustifolia (Verbanaceae) in Normoglycaemic and Alloxan-Induced Diabetic Rats. Pakistan Journal of Biological Sciences, 10: 137-141.

DOI: 10.3923/pjbs.2007.137.141

URL: https://scialert.net/abstract/?doi=pjbs.2007.137.141

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