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Pakistan Journal of Biological Sciences
  Year: 2006 | Volume: 9 | Issue: 7 | Page No.: 1287-1292
DOI: 10.3923/pjbs.2006.1287.1292
Effect of Video Display Terminal Radiations on Ion-transporting Adenosine Triphosphatase in Brain
Morteza Shahbazi-Moghadam and Nazly Mahdavi

Electric field (4400 V/m), magnetic field (B = 12 μT ), at zero frequency and electromagnetic magnetic field at 30 kHz and 92 μT, produced by video display terminals have been produced to observe how they affect ion transport processes and ATP (Adenosine Triphosphatase) splitting through changes in the activation of the membrane Na, K- ATPase in mousse brain. Both processes varied remarkably with magnetic and electromagnetic fields, while the variation with DC electric field was negligible. ATP splitting by Na, K-ATPase suspensions decreases for enzyme under normal conditions, with maximum effect at one hour of use of video display terminals. ATP splitting increases when the enzyme activity is lowered to less than half its optimal value by changes in temperature or ouabain concentration. These are because of the effect of the ionic currents on ion binding at the enzyme activation sites. Same mechanism could account for the effects of electromagnetic fields on cells, as the transmembrane enzyme can convey the effect of an extra cellular signal into the cell via ionic fluxes and the measured threshold field is within the range of reported biological effects. An oscillator similar to that of video display has been designed and constructed. The subjects were 60 mousses which were irradiated in a cage specially designed for our research purposes in different time of exposures. The results showed a good correlation between the time of exposure and the field intensities (R = 0.68, n = 60...., p<0.05). Present findings show that the specific activity decreases and is the minimum for 60 min of video display terminals usage and increases thereafter.
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How to cite this article:

Morteza Shahbazi-Moghadam and Nazly Mahdavi , 2006. Effect of Video Display Terminal Radiations on Ion-transporting Adenosine Triphosphatase in Brain. Pakistan Journal of Biological Sciences, 9: 1287-1292.

DOI: 10.3923/pjbs.2006.1287.1292






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