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Pakistan Journal of Biological Sciences
  Year: 2005 | Volume: 8 | Issue: 6 | Page No.: 855-859
DOI: 10.3923/pjbs.2005.855.859
 
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Different Concentration Selenium-modulated Action on Rat Dorsal Root Ganglion Neurons

Tong-Han Lan and Xian-Ming Liu

Abstract:
In present study, a concentration-dependent effect of Selenium on rat dorsal root ganglion neurons was characterized using whole-cell patch-clamp recording. Among about 52% of the cells tested, the amplitude of membrane ion current increased, after administration of Selenium. In the presence of 0.001 nM (nanomolar) Selenium, the reversal potential and membrane conductance were changed. The above-mentioned actions suggest that selenium may play a physiological role in regulating the excitatory action on mammalian neurons.
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How to cite this article:

Tong-Han Lan and Xian-Ming Liu , 2005. Different Concentration Selenium-modulated Action on Rat Dorsal Root Ganglion Neurons. Pakistan Journal of Biological Sciences, 8: 855-859.

DOI: 10.3923/pjbs.2005.855.859

URL: https://scialert.net/abstract/?doi=pjbs.2005.855.859

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