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Pakistan Journal of Biological Sciences
  Year: 2004 | Volume: 7 | Issue: 8 | Page No.: 1430-1432
DOI: 10.3923/pjbs.2004.1430.1432
 
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Effects of Aqueous Stem Bark Extract of Momordica balsamina Linn on Serum Electrolytes and Some Haematological Parameters in Normal and Alcohol Fed Rats

Matawalli A. Geidam, Issa Pakmam and Hajjagana Laminu

Abstract:
In the present study aqueous stem bark extract of Momordica balsamina was administered intragastrically to normal and alcohol fed rats to determine the effects of the extract on serum electrolytes and some haematological parameters. The stem bark extract  was administered for  two weeks  at a dose of 0.56 mg/100 g body weight. The parameters studied were the major electrolytes (Na+, K+, Cl- and HCO3-), glucose, albumen, total protein and some haematological parameters (RBC and WBC counts, PCV and haemoglobin). The results obtained showed that serum electrolytes levels were not significantly affected and there are no significant effects on haematological parameters (RBC counts, PCV and haemoglobin) except WBC counts. The stem bark extract produced significant (p<0.05) increases in WBC count values. This elevation of the white blood cells count following the administration of the extract may be an indication of a possible immune response of treated rats but the implication of this finding on WBC count remains to be explained.
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How to cite this article:

Matawalli A. Geidam, Issa Pakmam and Hajjagana Laminu , 2004. Effects of Aqueous Stem Bark Extract of Momordica balsamina Linn on Serum Electrolytes and Some Haematological Parameters in Normal and Alcohol Fed Rats. Pakistan Journal of Biological Sciences, 7: 1430-1432.

DOI: 10.3923/pjbs.2004.1430.1432

URL: https://scialert.net/abstract/?doi=pjbs.2004.1430.1432

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