Research Article

Histological Evidence of Retardation of Spermatogenesis in Mice in Experimentally Induced Fetal Alcohol Syndrome

J.E. Onu, D.N. Ezeasor and E.C. Ihemelandu

The effect of maternal alcohol consumption during pregnancy and lactation on the spermatogenesis in male offspring was studied in neonatal mice. Three groups of mice comprising 12 female and 3 male mice group were used. The offspring of group 1 served as control while those of groups 2 and 3 were exposed to 30% ethanol (^V/_V) prenatally and pre-and postnatally, respectively. At 6 weeks of age 10 male offspring were randomly selected from the three groups and sacrificed. Following sacrifice, the testes and cauda epididymis were carefully dissected out, fixed in Bouin`s fluid and prepared for routine histological examination. Examination of the seminiferous tubules showed delay in the development of spermatogenic cells as evidenced by few to no spermatozoa in the cauda epididymis of the alcohol-exposed groups.

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J.E. Onu, D.N. Ezeasor and E.C. Ihemelandu, 2003. Histological Evidence of Retardation of Spermatogenesis in Mice in Experimentally Induced Fetal Alcohol Syndrome. Pakistan Journal of Biological Sciences, 6: 1860-1863.

DOI: 10.3923/pjbs.2003.1860.1863

URL: https://scialert.net/abstract/?doi=pjbs.2003.1860.1863

Pakistan Journal of Biological Sciences

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Authors

J.E. Onu

D.N. Ezeasor

E.C. Ihemelandu

Keywords

Research Article

Histological Evidence of Retardation of Spermatogenesis in Mice in Experimentally Induced Fetal Alcohol Syndrome

How to cite this article

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