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Pakistan Journal of Biological Sciences
  Year: 2002 | Volume: 5 | Issue: 2 | Page No.: 189-191
DOI: 10.3923/pjbs.2002.189.191
 
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Antimicrobial Activity of Extracts and a Glycoside from Vanda roxburghii Br.

Farque Ahmed, Abu Sayeed, Anwarul Islam, S.M. Abdus Salam, Golam Sadik, M.A. Sattar and G.R.M. Astaq Mohal Khan

Abstract:
The petroleum ether, ethyl acetate and methanol extracts of Vanda roxburghii as well as glycoside, melianin (VR-1) isolated from it were screened for antimicrobial activity against a wide variety of bacteria and fungi. The ethyl acetate and methanol extracts showed moderate antibacterial activity against almost all the tested organisms. The compound melianin (VR-1) exhibited strong activity against all the tested organisms and produced zone of inhibition between 17 and 27 mm. The petroleum ether extract was found comparatively less active against the organisms. All the tested materials showed antifungal activity against Aspergillus fumigatus, Candida albicans, Hensinela californica and Rhizopus arijae. The minimum inhibitory concentrations (MIC) of melianin against Bacillus cereus, Bacillus subtilis, Escherichia coli and Shigella dysenteriae were 32, 64, 64 & 128 μg ml–1 respectively. The findings may provide the basis for traditional use of this plant in the treatment of infectious diseases.
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How to cite this article:

Farque Ahmed, Abu Sayeed, Anwarul Islam, S.M. Abdus Salam, Golam Sadik, M.A. Sattar and G.R.M. Astaq Mohal Khan, 2002. Antimicrobial Activity of Extracts and a Glycoside from Vanda roxburghii Br.. Pakistan Journal of Biological Sciences, 5: 189-191.

DOI: 10.3923/pjbs.2002.189.191

URL: https://scialert.net/abstract/?doi=pjbs.2002.189.191

COMMENTS
04 July, 2020
RADHIKA RAHEJA:
Dear Sir,
Would you please be able to send me spectral details of Melianin?
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