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Pakistan Journal of Biological Sciences
  Year: 2001 | Volume: 4 | Issue: 3 | Page No.: 244-246
DOI: 10.3923/pjbs.2001.244.246
 
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The Antinociceptive Effects of Extracts from Stichopus chloronotus Brandt
Ridzwan B.H., M.Z. Zarina , Kaswandi M.A. , M. Nadirah and A.F. Shamsuddin

Abstract:
The antinociceptive activities of several extracts (water, phosphate buffer solution, ethanol and methanol) of sea cucumber Stichopus chloronotus Brandt were evaluated in mice using the abdominal constriction and hot tail-flick test in comparison to morphine and normal saline being positive and negative control, respectively. The control group exhibited no significant effect whereas morphine sulphate (0.8 mg/kg) and all the extracts at various doses (10, 30, 50 mg/kg) reduced acetic acid-induced abdominal constriction.
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How to cite this article:

Ridzwan B.H., M.Z. Zarina , Kaswandi M.A. , M. Nadirah and A.F. Shamsuddin , 2001. The Antinociceptive Effects of Extracts from Stichopus chloronotus Brandt. Pakistan Journal of Biological Sciences, 4: 244-246.

DOI: 10.3923/pjbs.2001.244.246

URL: https://scialert.net/abstract/?doi=pjbs.2001.244.246

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