
	Pakistan Journal of Biological Sciences
	Year: 2000 \| Volume: 3 \| Issue: 10 \| Page No.: 1705-1707 DOI: 10.3923/pjbs.2000.1705.1707

Sumithion Induced Hepatic Injury in the Toads Bufo tibamicus

S. A. Sakr and A.M. Hijji

Abstract: The present work studied the effect of the organophosphate insecticide, sumithion on the liver of toads Bufo tibamicus. Feeding toads with a daily dose of sumithion (40 mg/kg body weight) for 10 days caused histological alterations in the liver. The normal structural organization of the hepatic acini was impaired, the hepatocytes showed cytoplasmic vacuolation and the blood vessels were congested. Moreover, elevations of transaminases (GOT, GPT) were recorded in the sera of treated animals. The obtained results collectively indicated that sumithion treatment induced liver injury in the toads.

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How to cite this article:

S. A. Sakr and A.M. Hijji, 2000. Sumithion Induced Hepatic Injury in the Toads Bufo tibamicus. Pakistan Journal of Biological Sciences, 3: 1705-1707.

DOI: 10.3923/pjbs.2000.1705.1707

URL: https://scialert.net/abstract/?doi=pjbs.2000.1705.1707

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