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Pharmacologia
  Year: 2016 | Volume: 7 | Issue: 4 | Page No.: 217-222
DOI: 10.5567/pharmacologia.2016.217.222
Antioxidant and Anti-inflammatory Activities of Platanus orientalis: An Oriental Plant Endemic to Kashmir Planes
Syed Irtiza, Gulzar A. Bhat, Mudasar Ahmad, Hilal A. Ganaie, Bashir A. Ganai, Azra N. Kamili, Seema Akbar and Mudasir A. Tantry

Abstract:
Background and Objectives: Platanus orientalis also called Oriental plane or Chinar or Boonyi (Platanaceae) is a large, deciduous tree, known for its longevity and spreading crown. The present work describes determination of antioxidant, anti-inflammatory and total phenol content of Platanus orientalis. Materials and Methods: Different extracts of the plant such as stem, root and leaves were prepared in different solvents such as chloroform, methanol and water. Results: Total phenol content in this plant reveal that methanol extract of Platanus orientalis root showed maximum free radical scavenging activity followed by methanol wood extract. Antioxidant activity of the plant extracts in this study reveal that it is methanol and chloroform extracts which showed above 50% inhibition in contrast to aqueous extracts. Anti-inflammatory activity of Platanus orientalis showed that aqueous wood extract of Platanus orientalis showed maximum activity in contrast to other extracts. With the help of acute toxicity test it was found that all the extracts are nontoxic at 2 g kg –1 b.wt. to Wistar rats. Conclusion: These finding provides some biological value of different extracts of Platanus orientalis for the use as antioxidant and anti-inflammatory agents. However, further investigation on isolation and purification of the bio-active molecules is needed to explore the exact mechanism of action of the Platanus orientalis extracts.
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How to cite this article:

Syed Irtiza, Gulzar A. Bhat, Mudasar Ahmad, Hilal A. Ganaie, Bashir A. Ganai, Azra N. Kamili, Seema Akbar and Mudasir A. Tantry, 2016. Antioxidant and Anti-inflammatory Activities of Platanus orientalis: An Oriental Plant Endemic to Kashmir Planes. Pharmacologia, 7: 217-222.

DOI: 10.5567/pharmacologia.2016.217.222

URL: https://scialert.net/abstract/?doi=pharmacologia.2016.217.222

 
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