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Pharmacologia

Year: 2015 | Volume: 6 | Issue: 6 | Page No.: 235-243
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Authors

M. Aktaruzzaman

M. S. Islam

M. M.R. Howlader

Keywords

Research Article

Effects of Three Different Modern Anthelmintics against Gastrointestinal Nematodiasis in Black Bengal Goats Prompting Hematological Parameters and Live Weight Studies

M. Aktaruzzaman, M. S. Islam and M. M.R. Howlader
Background and Objectives: This study aimed to evaluate the efficacy of ivermectin, levamisole HCl and albendazole against gastrointestinal nematodes on the basis of body weight of goats and hematological parameters like TEC, Hb, PCV, ESR and TLC in naturally infected goats of Government Goat Development Farm, Sylhet, Bangladesh. Methodology: The study included 50 black Bengal breed of which thirty were naturally infected and twenty of 13-15 month old irrespective of sex were randomly selected for this experiment on the basis of their weight and egg count and randomly divided into four equal groups A, B, C and D where each group consisted of 5 goats and goats of group D were kept as control group. One injectable ivermectin (200 μg kg-1 b.wt., S/C) preparations and two solid levamisole Hcl and albendazole (7.5 mg kg-1 b.wt., orally) preparations were used for positive control of group A, B and C. Before trials (day 0), blood samples and initial body weight were recorded. During the study period, the fecal and blood samples were collected and examined on 7th, 14th, 21st and 28th day using McMaster fecal egg counting method. Results: The results of the comparative efficacies of anthelmintic of ivermectin were 83.25%, followed by levamisole HCl 94.53% and albendazole 86.12%. After treatment, TEC, Hb and PCV were increased significantly (p<0.01 and p>0.05) in goats but ESR and TLC were decreased significantly (p<0.05 and p>0.01) in all treated goat and body weight was increased significantly (p<0.01) on day 28. Conclusion: The findings of the present study reveal that Ivermectin (A-mectin, injectable formulation), Levamisole (Levavet) and Albendazole (Almex-Vet) are effective for the reduction of EPG (eggs per gram) of gastrointestinal nematodes. Additional detailed studies are required to clarify the current status of the efficacy of the anthelmintic widely used in different agro ecologies, animal species and livestock management systems in Bangladesh.
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How to cite this article

M. Aktaruzzaman, M. S. Islam and M. M.R. Howlader, 2015. Effects of Three Different Modern Anthelmintics against Gastrointestinal Nematodiasis in Black Bengal Goats Prompting Hematological Parameters and Live Weight Studies. Pharmacologia, 6: 235-243.

URL: https://scialert.net/abstract/?doi=pharmacologia.2015.235.243

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