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Microbiology Journal

Year: 2012 | Volume: 2 | Issue: 1 | Page No.: 1-22
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Authors

M.M. Afifi

H.M. Atta

A.A. Elshanawany

U.M. Abdoul-Raouf

A.M. El-Adly

Keywords

Research Article

Identification of Luteomycin like Antibiotic Produced by Streptomyces tanashiensis AZ-C442 Isolated from Luxor Governorate at Upper Egypt

M.M. Afifi, H.M. Atta, A.A. Elshanawany, U.M. Abdoul-Raouf and A.M. El-Adly
A Streptomyces bacterium, designated AZ-C442 was isolated from a soil sample collected from Luxor governorate, Egypt. Phylogenetic analysis based on 16S rRNA gene sequences and culture characteristics demonstrated strain AZ-C442 affiliation to the genus Streptomyces tanashiensis. This strain exhibited inhibitory activity against gram-positive and gram-negative bacteria and unicellular and filamentous fungi by evaluation of optimum environmental and nutritional conditions. It was found that the Streptomyces tanashiensis AZ-C442 produced and excreted into the culture medium a large amount of the compound, which was isolated, purified and structurally characterized as known Luteomycin like antibiotic on the basis of combined spectral analyses which indicates a suggested impirical formula of C15H30N2O10. Luteomycin showed inhibitory effects against Staphylococcus aureus, Klebsiella pneumonia, Escherichia coli and Salmonella typhi, moreover, against Aspergillus flavus, Alternaria alternate and Saccharomyces cerevisiae.
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How to cite this article

M.M. Afifi, H.M. Atta, A.A. Elshanawany, U.M. Abdoul-Raouf and A.M. El-Adly, 2012. Identification of Luteomycin like Antibiotic Produced by Streptomyces tanashiensis AZ-C442 Isolated from Luxor Governorate at Upper Egypt. Microbiology Journal, 2: 1-22.

DOI: 10.3923/mj.2012.1.22

URL: https://scialert.net/abstract/?doi=mj.2012.1.22

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