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Journal of Pharmacology and Toxicology
  Year: 2011 | Volume: 6 | Issue: 3 | Page No.: 333-336
DOI: 10.3923/jpt.2011.333.336
 
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Impact of Curacron Toxicity on Lactate Dehydrogenase in the Serum of the Fish Cyprinus carpio

Baby Joseph and S. Justin Raj

Abstract:
The experiment was conducted on fish, Cyprinus carpio to study the effect of curacron on serum biomarker (LDH). Curacron is a organophosphate pesticide and is used by the farmers to protect their crops. This pesticide reaches to the aquatic ecosystem by many ways and affects the aquatic fauna. LC50 of Curacron for Cyprinus carpio has been calculated by the log-dose/probit regression line method and recorded as 0.38 ppm at 96 h. Three sub-lethal concentrations (0.1, 0.01 mL and 0.001 ml L-1) were selected to expose the fish for 1, 7, 14 and 21 days. Changes in enzyme activity were observed with all concentrations and exposure period. Lactate concentrations were significantly lower in the experimental group, compared with the control group. The above results of blood plasma profile indicate a marked cytotoxic and hepatotoxic effect of curacron in fishes.
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 RELATED ARTICLES:
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How to cite this article:

Baby Joseph and S. Justin Raj, 2011. Impact of Curacron Toxicity on Lactate Dehydrogenase in the Serum of the Fish Cyprinus carpio. Journal of Pharmacology and Toxicology, 6: 333-336.

DOI: 10.3923/jpt.2011.333.336

URL: https://scialert.net/abstract/?doi=jpt.2011.333.336

COMMENTS
22 November, 2011
M.S..Selvaraju:
Among those article has to provide some valuable research information for young and budding generation in the field of Toxicology. i appreciate and send me a copy of article
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