Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
Journal of Pharmacology and Toxicology
  Year: 2010 | Volume: 5 | Issue: 6 | Page No.: 262-274
DOI: 10.3923/jpt.2010.262.274
Evaluation of Safety and Immunotoxicity of Immunol, A Polyherbal Formulation in Rats
S.M. Sulaiman, Geetha Rajashekhar, P.J. Prakash, D.S. Singh and C. Saleem

Abstract:
Immunol, a polyherbal formulation was evaluated for its safety and effect on the immune system of rats. The rats were administered a single oral dose of 20 mL kg-1 b.wt. while others were given repeated doses of 1, 5 and 10 mL kg-1 b.wt., orally for 28 days. Immunol treatment did not elicit any abnormalities on the body weight gain, food consumption, neurological assessment, hematology and clinical chemistry parameters, organ weights, gross organ pathology and histopathology and humoral immunity, but it enhanced the cell mediated immunity. It was concluded that Immunol was safe at single oral dose of 20 mL kg-1 b.wt. and repeated dose of 10 mL kg-1 b.wt. in rats for 28 days.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    91-day Oral Toxicity Evaluation of a Herbal Preparation Used in the Management of Breast Tumour in Southwestern Nigeria using Mice
  •    Qualitative Analysis of the Pyrrolizidine Alkaloids from 11 Asteraceae and Boraginaceae Used in Traditional Medicine in Cote d’Ivoire
  •    Toxicological Evaluation of the Anti-Malarial Herb Cryptolepis sanguinolenta in Rodents
  •    Studies on the Toxicity of Ageratum conyzoides
  •    Acute Oral Toxicity Evaluation of Some Polyherbal Formulations in Albino Wistar Rats
  •    Evaluation of Preliminary Toxicity Studies on the Methanolic Leaves Extract of Tylophora asthmatica in Experimental Rats
How to cite this article:

S.M. Sulaiman, Geetha Rajashekhar, P.J. Prakash, D.S. Singh and C. Saleem, 2010. Evaluation of Safety and Immunotoxicity of Immunol, A Polyherbal Formulation in Rats. Journal of Pharmacology and Toxicology, 5: 262-274.

DOI: 10.3923/jpt.2010.262.274

URL: https://scialert.net/abstract/?doi=jpt.2010.262.274

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 

       

       

Curve Bottom