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Journal of Pharmacology and Toxicology

Year: 2008 | Volume: 3 | Issue: 5 | Page No.: 378-381
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Authors

V.M. Mounnissamy

S. Kavimani

V. Balu

S. Darlin Quine

Keywords

Research Article

Antipyretic Activity of Ethanol Extract of Cansjera rheedii J. Gmelin (Opiliaceae)

V.M. Mounnissamy, S. Kavimani, V. Balu and S. Darlin Quine
The antipyretic activity of ethanol (95%) extracts of Cansjera rheedii J. Gmelin aerial parts of the plant was evaluated against brewer`s yeast-induced pyrexia in rats to assess their antipyretic activity. Rectal temperatures were recorded before and after inducing pyrexia at interval of one hour to five hours. At the same time parallel experiments were run with a standard antipyretic paracetamol (100 mg kg-1) and control (Normal Saline 5 mL kg-1). Ethanol extract of Cansjera rheedii J. Gmelin at dose of 250 mg and 500 mg kg-1 body weight showed the antipyretic activity significantly (p<0.001) compared to that of control.
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