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Journal of Pharmacology and Toxicology

Year: 2007 | Volume: 2 | Issue: 8 | Page No.: 709-717
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Authors

R. Mahesh

V. Hazeena Begum

Keywords

Research Article

Modulatory Role of Terminalia chebula on Erythrocyte Defenses in Young and Aged Rats

R. Mahesh and V. Hazeena Begum
The present study was aimed to evaluate the oxidants, enzymatic and nonenzymatic antioxidants, glycoproteins and membrane adenosine triphosphatases (ATPases). The increased levels of oxidants and decreased levels of enzymatic, nonenzymatic antioxidants, glycoproteins and ATPases were observed in erythrocytes of aged rats. After administration of Terminalia chebula, the levels were reverted to normal in aged rats. These results indicate that the administration of T. chebula acts as a free radical scavenger with potential antioxidant effects in erythrocytes of aged rats.
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