Subscribe Now Subscribe Today
Science Alert
 
FOLLOW US:     Facebook     Twitter
Blue
   
Curve Top
Journal of Pharmacology and Toxicology
  Year: 2007 | Volume: 2 | Issue: 6 | Page No.: 574-579
DOI: 10.3923/jpt.2007.574.579
Antibacterial Activity of Extracts of Piper longum
P.D. Lokhande, K.R. Gawai , K.M. Kodam , B.S. Kuchekar , A.R. Chabukswar and S.C. Jagdale

Abstract:
Dry roots of the plant Piper longum were extracted with n-hexane. The constituents were isolated and purified by column chromatography. The structures of the isolated constituents were confirmed by spectral analysis. The isolated constituents and n-hexane extract were found to show varying degree of antibacterial activity against all the tested bacteria. However, the aqueous extract did not show antibacterial activity against the tested bacteria. The isolated constituents were found to show better activity profile than the n-hexane extract, which indicates that the isolated constituents might be responsible for the antibacterial activity. The Minimum Inhibitory Concentration (MIC) value of piperine against Bacillus cereus and Escherichia coli was found to be 12.5 mg mL-1.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    In vitro Evaluation of Antibacterial Activities of Crude Extracts of Withania somnifera (Ashwagandha) to Bacterial Pathogens
How to cite this article:

P.D. Lokhande, K.R. Gawai , K.M. Kodam , B.S. Kuchekar , A.R. Chabukswar and S.C. Jagdale , 2007. Antibacterial Activity of Extracts of Piper longum . Journal of Pharmacology and Toxicology, 2: 574-579.

DOI: 10.3923/jpt.2007.574.579

URL: https://scialert.net/abstract/?doi=jpt.2007.574.579

 
COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 

       

       

Curve Bottom