Subscribe Now Subscribe Today
Science Alert
 
Blue
   
Curve Top
Journal of Pharmacology and Toxicology
  Year: 2007 | Volume: 2 | Issue: 3 | Page No.: 290-294
DOI: 10.3923/jpt.2007.290.294
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Assessment of the Role of the μ Opioid Receptor in Ethanol-Induced Hyperprolactinemia in Mice

Richard Stripp and Kelly Brinsko

Abstract:
The purpose of this study was to examine the role of the endogenous opiate system, specifically the opiate receptor subtypes, in response to ethanol induced prolactin secretion in male Swiss-Webster mice. In order to determine the role of μ opiate receptors in ethanol induced hyperprolactinemia, animals were treated with ethanol with and without pretreatment with the opiate receptor antagonist β-Funaltrexamine. Additional animals were also treated with β-Endorphin under similar conditions as a positive control of opiate receptor activity and prolactin secretion. Opiate receptor antagonists successfully ameliorated ethanol induced hyperprolactinemia. This research could provide insight into ethanol`s role in prolactin secretion and indirectly monitor changes in reproductive and immunological functions.
PDF Fulltext XML References Citation Report Citation
How to cite this article:

Richard Stripp and Kelly Brinsko, 2007. Assessment of the Role of the μ Opioid Receptor in Ethanol-Induced Hyperprolactinemia in Mice. Journal of Pharmacology and Toxicology, 2: 290-294.

DOI: 10.3923/jpt.2007.290.294

URL: https://scialert.net/abstract/?doi=jpt.2007.290.294

COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 

Curve Bottom