
	Journal of Pharmacology and Toxicology
	Year: 2007 \| Volume: 2 \| Issue: 3 \| Page No.: 290-294 DOI: 10.3923/jpt.2007.290.294

Assessment of the Role of the μ Opioid Receptor in Ethanol-Induced Hyperprolactinemia in Mice

Richard Stripp and Kelly Brinsko

Abstract: The purpose of this study was to examine the role of the endogenous opiate system, specifically the opiate receptor subtypes, in response to ethanol induced prolactin secretion in male Swiss-Webster mice. In order to determine the role of μ opiate receptors in ethanol induced hyperprolactinemia, animals were treated with ethanol with and without pretreatment with the opiate receptor antagonist β-Funaltrexamine. Additional animals were also treated with β-Endorphin under similar conditions as a positive control of opiate receptor activity and prolactin secretion. Opiate receptor antagonists successfully ameliorated ethanol induced hyperprolactinemia. This research could provide insight into ethanol`s role in prolactin secretion and indirectly monitor changes in reproductive and immunological functions.

PDF Fulltext XML References Citation Report Citation

How to cite this article:

Richard Stripp and Kelly Brinsko, 2007. Assessment of the Role of the μ Opioid Receptor in Ethanol-Induced Hyperprolactinemia in Mice. Journal of Pharmacology and Toxicology, 2: 290-294.

DOI: 10.3923/jpt.2007.290.294

URL: https://scialert.net/abstract/?doi=jpt.2007.290.294

COMMENT ON THIS PAPER

Navigation


		Online First
		Current Issue
		Previous Issues
		Editorial Board
		Submit a Manuscript
		Guide to Authors
		Subscribe to E-alerts

Indexed In


		ASCI-Database
		Asian Digital Library
		Cambridge Scientific Abstract
		Chemical Abstract Services
		Google Scholar

Science Alert