The Anti-inflammatory, Anti-pyretic and Wound Healing Activities of Cocos nucifera (MATAG Types) Fresh Juice and Kernel Extract in Experimental Animals


	Journal of Pharmacology and Toxicology
	Year: 2006 \| Volume: 1 \| Issue: 6 \| Page No.: 516-526 DOI: 10.3923/jpt.2006.516.526

The Anti-inflammatory, Anti-pyretic and Wound Healing Activities of Cocos nucifera (MATAG Types) Fresh Juice and Kernel Extract in Experimental Animals

Z.A. Zakaria, I. Reezal, A.M. Mat Jais, M.N. Somchit, M.R. Sulaiman, A.H.I. Marmin, H. Sidek, S.H. Husin, M.H.A. Rahim and L. Abdul Rahman

Abstract: The present study was carried out to evaluate the potential of C. nucifera as antipyretic, anti-inflammatory and wound healing agents. The fresh juice of C. nucifera (FJCN) was directly used while its aqueous kernel extract (AKCN) was obtained after 72 h soaking of 1:2 (w/v) fresh kernel in 2:1 (v/v) chloroform:methanol. The extracts, in the concentrations/strengths of 10, 50 and 100%, were used in the anti-pyretic and anti-inflammatory studies while those in the concentration of 100% were used only in the wound healing study. The fresh juice and aqueous kernel extract of C. nucifera exhibited significant (p<0.05) anti-inflammatory and antipyretic activities and promote wound healing with the latter producing a more effective effects in all assays used. This finding has scientifically supported the folkloric used of C. nucifera in the treatment of inflammation, pyrexia and wound.

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How to cite this article:

Z.A. Zakaria, I. Reezal, A.M. Mat Jais, M.N. Somchit, M.R. Sulaiman, A.H.I. Marmin, H. Sidek, S.H. Husin, M.H.A. Rahim and L. Abdul Rahman, 2006. The Anti-inflammatory, Anti-pyretic and Wound Healing Activities of Cocos nucifera (MATAG Types) Fresh Juice and Kernel Extract in Experimental Animals. Journal of Pharmacology and Toxicology, 1: 516-526.

DOI: 10.3923/jpt.2006.516.526

URL: https://scialert.net/abstract/?doi=jpt.2006.516.526

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