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Journal of Pharmacology and Toxicology
  Year: 2006 | Volume: 1 | Issue: 3 | Page No.: 284-288
DOI: 10.3923/jpt.2006.284.288
 
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Response of Wistar Rats to Low Levels of Dietary Allium cepa, Allium sativum and Sodium Selenite

E.H. Abdel Gadir, W.S. Abdel Gadir and S.E.I. Adam

Abstract:
Allium cepa and Allium sativum were fed to male Wistar rats at 2 or 6% of standard diet for 4 weeks. Sodium selenite was also fed to rats at 1ppm and 3 ppm for a similar period. Two percent A. cepa and 2% A. sativum or 1 ppm sodium selenite were not toxic to rats. Impairment of growth and hepatonephropathy were observed in the rats fed diets containing 6% A. cepa and 6% A. sativum or 3 ppm sodium selenite. These changes were correlated with alterations in serum aspartate aminotransferase (AST) alanine aminotransferase, (ALT) and alkaline phosphatase (ALP) activities and total protein, albumin, cholesterol and urea concentrations and hematology.
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How to cite this article:

E.H. Abdel Gadir, W.S. Abdel Gadir and S.E.I. Adam , 2006. Response of Wistar Rats to Low Levels of Dietary Allium cepa, Allium sativum and Sodium Selenite. Journal of Pharmacology and Toxicology, 1: 284-288.

DOI: 10.3923/jpt.2006.284.288

URL: https://scialert.net/abstract/?doi=jpt.2006.284.288

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