Subscribe Now Subscribe Today
Science Alert
 
Blue
   
Curve Top
Journal of Plant Sciences
  Year: 2007 | Volume: 2 | Issue: 3 | Page No.: 293-301
DOI: 10.3923/jps.2007.293.301
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Protective Role of Momordica charantia Seeds Extract on Membrane Bound ATPases and Lysosomal Hydrolases in Rats with Streptozotocin Diabetes

D. Sathishsekar and S. Rajasekaran

Abstract:
The aim of the present study was to examine the effect of an aqueous extract from Momordica charantia seed(s) on membrane bound ATPases and lysosomal hydrolases in the liver and kidney of streptozotocin (STZ)-induced diabetic rats. The rats treated with STZ showed a significant alterations in the activities of membrane bound ATPases and lysosomal hydrolases in the liver and kidney. Oral administration of Momordica charantia seed(s) extract at a dose of 150 mg kg-1 body weight rat-1 day-1 to STZ-induced diabetic rats for a period of 30 days significantly restored the alterations in enzymes activity to near normal level. These results were compared with glibenclamide, a reference drug. Thus, the present study confirms that Momordica charantia seed(s) extract possesses a significant protective effect on membrane bound ATPases and lysosomal hydrolases.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Effect of Momordica charantia Fruit Extract on Normal and Alloxan-Diabetic Rats
How to cite this article:

D. Sathishsekar and S. Rajasekaran , 2007. Protective Role of Momordica charantia Seeds Extract on Membrane Bound ATPases and Lysosomal Hydrolases in Rats with Streptozotocin Diabetes. Journal of Plant Sciences, 2: 293-301.

DOI: 10.3923/jps.2007.293.301

URL: https://scialert.net/abstract/?doi=jps.2007.293.301

COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 
 
 

Curve Bottom