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Research Journal of Parasitology
  Year: 2007 | Volume: 2 | Issue: 2 | Page No.: 94-98
DOI: 10.3923/jp.2007.94.98
 
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Antiplasmodial Activity of Ethanolic Root Extract of Telfairia occidentalis

Okokon J. E., A. J. Ekpo and O. A. Eseyin

Abstract:
The in vivo antiplasmodial activity of the ethanol root extract of Telfairia occidentalis grown particularly for the leaf and seed in Niger Delta region of Nigeria was evaluated in Plasmodium berghei infected mice. Telfairia occidentalis (200-600 mg kg-1 day-1) exhibited significant (p<0.05) blood schizonticidal activity both in 4 day early infection test and in established infection with a considerable mean survival time comparable to that of the standard drug, chloroquine, 5 mg kg-1 day-1. The leaf extract possesses significant (p<0.05) antiplasmodial activity which can be exploited in malarial chemotherapy.
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How to cite this article:

Okokon J. E., A. J. Ekpo and O. A. Eseyin, 2007. Antiplasmodial Activity of Ethanolic Root Extract of Telfairia occidentalis. Research Journal of Parasitology, 2: 94-98.

DOI: 10.3923/jp.2007.94.98

URL: https://scialert.net/abstract/?doi=jp.2007.94.98

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