Subscribe Now Subscribe Today
Science Alert
 
Blue
   
Curve Top
Journal of Medical Sciences
  Year: 2013 | Volume: 13 | Issue: 6 | Page No.: 471-476
DOI: 10.3923/jms.2013.471.476
 
Facebook Twitter Digg Reddit Linkedin StumbleUpon E-mail

Biological Activity of Methanolic Extract of Waltheria indica Roots

Raga Eltayeb Osman, Elamin Ibrahim Elnima and Mohammed Elfatih Ahmed Omer

Abstract:
Waltheria indica used by traditional healer in Sudan for treatment of many diseases. In this study antibacterial activity, toxicological and pharmacological screen of methanolic extracts of Weltheria indica roots was reported. One hundred eighty clinical isolates were obtained from diabetic wound infection, 30 Escherichia coli, 15 Klebsiella pneumoniae, 45 Proteus sp. 15 Pseudomonas aeruginosa, 60 Staphylococcus aureus and 15 Staphylococcus epidermidis. Cup-plate method used for antibacterial activity and the extract had an inhibitory effect against (91.7%) of the isolates. In the toxicity studies the results indicate that the LD50 of the extracts was more than 2000 mg kg-1. The extract had no effect on smooth muscle and skeletal muscle. The result of this study indicated that the methanolic extract of Waltheria indica roots with high antibacterial activity. In the toxicity study the result indicate that LD50 of the extract was more than 2000 mg kg-1 and the pharmacology study indicated at least the safety of the extract regarding the studied tissues.
PDF Fulltext XML References Citation Report Citation
 RELATED ARTICLES:
  •    Sedative and Anticonvulsant Effects of Ethyl Acetate Fraction of Waltheria indica in Mice
How to cite this article:

Raga Eltayeb Osman, Elamin Ibrahim Elnima and Mohammed Elfatih Ahmed Omer, 2013. Biological Activity of Methanolic Extract of Waltheria indica Roots. Journal of Medical Sciences, 13: 471-476.

DOI: 10.3923/jms.2013.471.476

URL: https://scialert.net/abstract/?doi=jms.2013.471.476

COMMENT ON THIS PAPER
 
 
 

 

 
 
 
 
 
 
 
 
 

 
 
 
 
 
 
 

Curve Bottom