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Journal of Medical Sciences
  Year: 2011 | Volume: 11 | Issue: 3 | Page No.: 138-144
DOI: 10.3923/jms.2011.138.144
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The Effect of Hydroalcholic Nettle (Urtica dioica) Extracts on Some Cardiovascular Risk Factors in Patients With Type 2 Diabetes

N. Namazi, A. Tarighat Esfanjani, M. Asghari and A. Bahrami

Type 2 diabetes is a metabolic disorder which is strongly associated with cardiovascular risk and requires intervention to improve glycemic control and other cardiovascular risk factors. In this study, hydro alcoholic extract of Nettle (Urtica dioica) on some cardiovascular risk factors in type 2 diabetic patients were studied. A randomized single-blind clinical trial of 50 men and women with type 2 diabetes aged 52.39±13.75 years was conducted. Patients were adjusted by age, sex and duration of diabetes, then randomly divided into an intervention and control groups, they received, 100 mg kg-1 day-1 nettle extract or placebo in 3 portions for 8 weeks. Fasting Blood Sugar (FBS), glycated Hemoglobin (HbA1C), Fasting Insulin concentration, Total Cholesterol (TC), Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL), Triglycerides (TG), systolic blood pressure(SBP), Diastolic blood pressure (DBP) were measured, TC/HDL-cholesterol, LDL/ HDL cholesterol ratio , Log (TG/HDL-c) and Insulin Resistance were calculated, at the beginning and end of the study. The data were analyzed by SPSS version 18, p<0.05 was considered significant in all measurement. After 8 weeks, FBS ,HbA1C , TG , Log (TG /HDL-c) and SBP showed a significant decrease and HDL-cholesterol showed a significant increase in the intervention group compared to the control group (p<0.05). The findings of this study suggest that the hydro alcoholic extract of nettle has a beneficial effect on FBS, HbA1C, TG, HDL-c concentration, Log (TG /HDL-c) and SBP in patients with type 2 diabetes after eight weeks intervention.
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  •    A Systematic Review about Effects of Aerial Portions of Urtica dioica (Nettle) on Some Cardiovascular Risk Factors in Diabetes Mellitus
  •    The Effect of Hydro Alcoholic Nettle (Urtica dioica) Extract on Oxidative Stress in Patients with Type 2 Diabetes: A Randomized Double-blind Clinical Trial
  •    Protective Effects of Green tea (Camelia sinensis), Hypericum perforatum and Urtica dioica on Hepatic Injury and Lymphocyte DNA Damage Induced by Carbon Tetrachloride in Wistar Rats
  •    The Protective Activity of Urtica dioica Leaves on Blood Glucose Concentration and β-cells in Streptozotocin-Diabetic Rats
  •    Chronic Effect of the Hydroalcholic Extract of Urtica dioica Leaves on Regeneration of ß-cells of Hyperglycemic Rats
  •    Role of Diet, Nutrients, Spices and Natural Products in Diabetes Mellitus
  •    Effects of Nitric Oxide on Glucose Transport: in vivo and in vitro Studies
How to cite this article:

N. Namazi, A. Tarighat Esfanjani, M. Asghari and A. Bahrami, 2011. The Effect of Hydroalcholic Nettle (Urtica dioica) Extracts on Some Cardiovascular Risk Factors in Patients With Type 2 Diabetes. Journal of Medical Sciences, 11: 138-144.

DOI: 10.3923/jms.2011.138.144






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