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Journal of Medical Sciences

Year: 2008 | Volume: 8 | Issue: 7 | Page No.: 660-664
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Authors

M.A. Abosedira

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Research Article

Adding Clonidine or Dexmedetomidine to Lidocaine During Bier`s Block: A Comparative Study

M.A. Abosedira
This prospective randomised double- blinded study was designed to compare the effects of adding either clonidine or dexmedetomidine to lidocaine during Bier`s block. Forty ASA I or II patients scheduled for elective upper limb body surface surgery under Bier`s block were recruited. Bier`s block was achieved using lidocaine in to which either dexmedetomidine 1 μg kg-1 or clonidine 1 μg kg-1 was added. There was no significant difference between the two groups regarding the onset or regression of both the sensory and motor blockades. Intra-operatively, there was a significant reduction in the number of patients requiring analgesia and its consumed amount in the Dexmedetomidine group (0% and 0 μg, respectively) compared to the Clonidine group (40% and 27±43 μg, respectively). Similarly, in the post-operative period there was a reduction in the number of patients requiring analgesia and its consumed amount in the Dexmedetomidine group (5% and 2.5±11 μg, respectively) compared to the Clonidine group (35% and 32±24.5 μg, respectively). The quality of anaesthesia was significantly better in the Dexmedetomidine group compared to the Clonidine group. Patients in the Dexmedetomidine group were more sedated briefly post-operatively. This study reveals that, adding dexmedetomidine to lidocaine during Bier`s block is better than adding clonidine.
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