Thyrotoxicsis has proved to be a challenging and intresting disorder. It can present in many ways though vomiting is uncommon as a main presenting symptom, which may lead to a delay in diagnosis. We are reporting a 74 years old male who presented with persistent vomiting, nausea and 10 kg weight loss. Investigations for causes of vomiting were negative except for hyperthyroidism. His symptoms resolved after treatment with carbimazole and B Blockers. Recurrence of thyrotoxicosis and vomiting occurred just after Radioiodine ablation therapy. To the best of our knowledge, this is the first case of thyrotoxic vomiting in a male patient of this age group, in addition to recurrence of thyrotoxic vomiting post radioiodine ablation therapy.