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Journal of Medical Sciences
  Year: 2007 | Volume: 7 | Issue: 2 | Page No.: 233-237
DOI: 10.3923/jms.2007.233.237
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Cholecystitis and its Risk Factors among Patients Undergoing Coronary Artery Bypass Grafting

Daryoush Javidi and Masih Shafa

The aim of this study was to assess the incidence of cholecystitis and its risk factors in patients undergoing Coronary Artery Bypass Grafting (CABG). In a cohort study, 574 patients undergoing CABG in Dr. Shariati Hospital from March 2003 to March 2004 were enrolled. In patients with cholecystitis signs and symptoms, ultrasonography and Liver Function Tests (LFTs) were performed. All the patients were followed for six months following the surgery. In 6 patients (1.06%) cholecystitis occurred, all during hospitalization. There were no significant differences in mean of age, BMI, CPB and cross clamp time, both sexes and patients with three vessels involvement and low cardiac output frequencies between patients with or without cholecystitis. In bivariate analysis, Frequency of patients with diabetes (83.33 vs. 12.16% with OR 36.10; 95% CI 4.16-313.67), hyperlipidemia (83.33 vs. 29.87% with OR 11.74; 95% CI 1.36-101.23) and postoperative biliary colic (83.33 vs. 3.58% with OR 70.54; 95% CI 8.03-619.53) were significantly higher in patients with cholecystitis than others. Also elevation of LFTs, Inotropic and IABP usage were significantly higher in patients with cholecystitis (All p = 0.01). When all variables were modeled using multivariable logistic regression analysis, a significant association was revealed between diabetes mellitus and post CABG cholecystitis (p = 0.01). All the patients with cholecystitis were treated by medical strategies including IV fluids, GI resting and broad spectrum antibiotics and no patients need surgical interventions. The presence of preoperative diabetes, hyperlipidemia, postoperative biliary colic, inotropic usage, elevation of LFTs and IABP could be significantly more frequent in patients with postoperative cholecystitis, although in multivariable analysis, diabetes mellitus was only detected as a significant risk factor of post CABG cholecystitis. Medical treatments for management of post-CABG cholecystitis carry acceptable results, advocating more studies.
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How to cite this article:

Daryoush Javidi and Masih Shafa, 2007. Cholecystitis and its Risk Factors among Patients Undergoing Coronary Artery Bypass Grafting. Journal of Medical Sciences, 7: 233-237.

DOI: 10.3923/jms.2007.233.237






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