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Journal of Medical Sciences
  Year: 2007 | Volume: 7 | Issue: 8 | Page No.: 1354-1357
DOI: 10.3923/jms.2007.1354.1357
 
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Improved Regeneration of Injured Sciatic Nerve of Rats by He-Ne Laser

Nasrin Takzare, Mir-jamal Hosseini , Mohammad Barbarestani , Azam Bakhtiarian , Hamid Reza Foroutan , Bahram Montazeri , Hamid Reza Kangarlou and Alireza Takzare

Abstract:
Inability of the neural tissue to regenerate in response to trauma and the disability which the result has prompted a lot of effort in search for new means of neural rehabilitation. Low-energy Helium-Neon laser (He-Ne laser) irradiation has been proposed as a sensible choice. Low-energy laser therapy in specific wavelengths and affluence maintains the electrophysiological activity of injured peripheral nerve in rat and accelerating regeneration of the injured nerve. We studied the effect of low level laser irradiation (He-Ne laser) on regeneration of injured sciatic nerve of rats. In the current experiment, sciatic nerves of 20 adult rats were crushed surgically. The subjects were randomly assigned into case and control groups. The cases received daily laser irradiation (λ = 650 nm) for 4 min. The muscular function of the rats was tested by angle board each 3 days, since the 3rd day of post operation. On the 27th day, all the rats were sacrificed and the manipulated sciatic nerves were excised and studied histologically. The results showed significant improvement of neural structure and muscular function in laser treated rats over the controls, as revealed by angle board testing and microscopic examination. It seems that low-energy lasers can reduce the load of infection at the operation field, tissue inflammation and post operation pain. This study show that low-energy He-Ne laser greatly restores crushed sciatic nerves in rats and can be considered for clinical trails.
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How to cite this article:

Nasrin Takzare, Mir-jamal Hosseini , Mohammad Barbarestani , Azam Bakhtiarian , Hamid Reza Foroutan , Bahram Montazeri , Hamid Reza Kangarlou and Alireza Takzare , 2007. Improved Regeneration of Injured Sciatic Nerve of Rats by He-Ne Laser. Journal of Medical Sciences, 7: 1354-1357.

DOI: 10.3923/jms.2007.1354.1357

URL: https://scialert.net/abstract/?doi=jms.2007.1354.1357

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